石墨烯新型灸贴治疗慢性腰痛的临床观察

Clinical efficacy of a new graphene moxibustion patch in the treatment of chronic low back pain

目的观察和评价石墨烯新型灸贴治疗慢性腰痛的临床疗效,确定其最佳的贴敷时长。方法按照随机数字表法将100例慢性腰痛患者分为治疗2 h组、治疗4 h组、治疗6 h组、治疗8 h组和对照组。治疗2 h组、治疗4 h组、治疗6 h组、治疗8 h组分别使用石墨烯新型灸贴贴敷2、4、6、8 h,对照组使用空白穴贴贴敷6 h。比较各组治疗前后的奥斯威斯特里功能障碍指数评分(Oswestry Dysfunction Index,ODI)、日本骨科协会评估治疗评分(Japanese Orthopaedic Association Scores,JOA)、罗兰-莫里斯功能障碍问卷(Roland-Morris Disability Questionnaire,RMDQ)、日常生活能力评分(Daily Living Ability,ADL)和阿是穴的红外线温度。结果不同贴敷时间的石墨烯新型灸贴均可以明显降低慢性腰痛患者ODI评分和RMDQ评分,明显升高患者的JOA评分、ADL评分和局部阿是穴温度。组间比较发现,石墨烯新型灸贴贴敷6 h后的ODI评分、JOA评分、RMDQ评分以及阿是穴局部温度的改善明显优于贴敷2 h与4 h,贴敷6 h与贴敷8 h后各项评分改善程度无明显差异;在ADL评分改善方面,贴敷4 h、6 h及8 h明显优于贴敷2 h,其改善程度随时间延长具有一定的上升趋势。结论石墨烯新型灸贴的疗效随着贴敷时间延长存在量效累积,其中以贴敷6 h效果最佳。

Objective To observe and evaluate the clinical efficacy of a new graphene moxibustion patch in the treatment of chronic low back pain and to determine its optimal duration of application.Methods A total of 100 patients with chronic low back pain were divided into a 2-hour treatment group,a 4-hour treatment group,a 6-hourtreatment group,an 8-hour treatment group and a control group according to the random number table method.The 2-hour treatment group,4-hour treatment group,6-hour treatment group,8-hour treatment group were applied with the new graphene moxibustion paste for 2 hours,4 hours,6 hours and 8 hours,respectively,while the control group was applied with a blank point paste for 6 hours.The Oswestry Dysfunction Index(ODI),Japanese Orthopaedic Association Scores(JOA),Roland-Morris Disability Questionnaire(RMDQ),Daily Living Ability(ADL),and infrared temperature of the Ashi point were compared before and after treatment in each group.Results The graphene moxibustion paste with different duration of application for the treatment of low back pain significantly reduced the ODI score and RMDQ score,and significantly increased the JOA score,ADL score and local temperature of the Ashi acupoint.The improvement of ODI score,JOA score,RMDQ score and local temperature of Ashi point was significantly better after 6 hours of application than that after 2 hours and 4 hours of application,while there was no significant difference between 6 hours and 8 hours of application.The improvement of ADL score after 4 hours,6 hours and 8 hours of application was significantly better than that of 2 hours of application,and showed an upward trend with time.Conclusion The efficacy of the new graphene moxibustion patch is cumulative with the prolongation of the application time,among which i best effect is achieved with 6 hours ofapplication.