血清AMH检验在多囊卵巢综合征中的价值研究

Study on the value of serum AMH test in polycystic ovary syndrome

目的探究多囊卵巢综合征(PCOS)诊断行血清抗苗勒管激素(AMH)检验的价值。方法选取240例多囊卵巢综合征患者作为观察组,并根据雄性激素睾酮水平设为高雄激素(>2.6 nmol/L,140例)、非高雄激素(≤2.6 nmol/L,100例)两个亚组。另选取同期本院体检健康女性240例作为对照组。两组进行血清AMH水平测定,比较各组AMH水平。结果观察组血清AMH水平(9.02±3.48)ng/ml明显高于对照组的(3.17±1.23)ng/ml,差异有统计学意义(P<0.05)。高雄激素组血清AMH水平明显高于非高雄激素组,差异有统计学意义(P<0.05)。结论多囊卵巢综合征患者血清AMH水平呈高表达状态,同时高雄激素患者血清AMH存在明显上升,可将血清AMH检验作为临床诊断多囊卵巢综合征的可靠依据之一。

Objective To explore the value of serum anti-mullerian hormone(AMH)test in the diagnosis of polycystic ovary syndrome.Methods 240 patients with polycystic ovary syndrome were selected as the observation group,and were divided into two subgroups according to the level of male hormone testosterone:high androgen(>2.6 nmol/L,140 cases)and non-high androgen(<2.6 nmol/L,100 cases).Another 240 healthy females were selected as the control group.Serum AMH levels were measured and compared between the two groups.Results Serum AMH level in observation group(9.02±3.48)ng/ml was significantly higher than that in control group(3.17±1.23)ng/ml,and the difference was statistically significant(P<0.05).The serum AMH level of high androgen group was significantly higher than that of non-high androgen group,and the difference was statistically significant(P<0.05).Conclusion The serum AMH level is highly expressed in patients with polycystic ovary syndrome,and the serum AMH level is significantly increased in patients with hyperandrogen.Serum AMH test can be used as one of the reliable bases for clinical diagnosis of polycystic ovary syndrome.