不同方法颞浅动脉旁皮下注射复方樟柳碱在缺血性视神经病变患者中的效果比较

Effects of different methods of subcutaneous injection of compound anisodine beside superficial temporal arteries in patients with ischemic optic neuropathy

目的探讨不同方法颞浅动脉旁皮下注射复方樟柳碱在缺血性视神经病变患者中的效果。方法选取江南大学附属中心医院2019年1月至6月收治的180例缺血性视神经病变患者进行随机对照试验,采用随机数字表法分为对照组与研究组,各90例。对照组男45例,女45例,年龄40~78(60.36±9.12)岁。研究组男46例,女44例,年龄39~78(60.12±9.05)岁。对照组采取常规皮下注射法,研究组采取改良颞浅动脉旁皮下注射复方樟柳碱。对比两组患者注射部位的疼痛程度、焦虑程度、护理满意度以及并发症发生情况。统计学方法采用χ^(2)检验、秩和检验。结果治疗后1个月,研究组疼痛程度均小于对照组,两组注射后疼痛程度等级比较,差异有统计学意义(Z=5.852,P<0.05)。治疗后1个月,研究组与对照组注射后轻度、中度、重度焦虑程度比较[66.67%(60/90)比24.44%(22/90)、24.44%(22/90)比50.00%(45/90)、8.89%(8/90)比25.56%(23/90)],差异均有统计学意义(χ^(2)=32.344、12.577、8.768,均P<0.05)。研究组的总满意度为92.22%(83/90),高于对照组[74.44%(67/90)],差异有统计学意义(χ^(2)=10.240,P<0.05)。随访6个月,两组并发症总发生率比较,研究组低于对照组[2.22%(2/90)比11.11%(10/90)],差异有统计学意义(χ^(2)=5.714,P<0.05)。结论改良颞浅动脉旁皮下注射复方樟柳碱能明显减轻患者疼痛和焦虑情绪,提高护理满意度,有效降低并发症总发生率。

Objective To explore the effects of different methods of subcutaneous injection of compound anisodine beside the superficial temporal arteries in patients with ischemic optic neuropathy.Methods One hundred and eighty patients with ischemic optic neuropathy admitted to Central Hospital Affiliated to Jiangnan University from January to June 2019 were selected for the randomized controlled trial.They were divided into a control group and a study group by the random number table method,with 90 cases in each group.There were 45 males and 45 females in the control group;they were 40-78(60.36±9.12)years old.There were 46 males and 44 females in the study group;they were 39-78(60.12±9.05)years old.The control group received routine subcutaneous injection,while the study group received modified subcutaneous injection of compound anisodine beside the superficial temporal arteries.The degrees of pain,anxiety,and nursing satisfaction and incidences of complications were compared between the two groups.χ^(2) and rank sum tests were applied.Results One month after the treatment,the pain degree of the study group was lower than that of the control group;there was a statistical difference in the pain grade between the two groups(Z=5.852,P<0.05).One month after the treatment,there were statistical differences in the mild,moderate,and severe anxiety between the study group and the control group[66.67%(60/90)vs.24.44%(22/90),24.44%(22/90)vs.50.00%(45/90),and 8.89%(8/90)vs.25.56%(23/90);χ^(2)=32.344,12.577,and 8.768;all P<0.05].The satisfaction of the study group was higher than that of the control group[92.22%(83/90)vs.74.44%(67/90)],with a statistical difference(χ^(2)=10.240,P<0.05).After 6 months'follow-up,the total incidence of complications of the study group was lower than that of the control group[2.22%(2/90)vs.11.11%(10/90)],with a statistical difference(χ^(2)=5.714,P<0.05).Conclusion The modified subcutaneous injection of compound anisodine beside the superficial temporal arteries can significantly reduce the patients'pain and anxiety,improve nursing satisfaction,and effectively reduce the incidence of complications.