微流控技术在病原微生物检测中的研究进展

Research Progress in Microfluidic Technology in the Detection of Pathogenic Microorganisms

快速、准确地检测病原微生物对于疫情防控和保障人民生命健康具有重大意义。近几年,研究者们通过合理地设计微流控芯片,将微流控技术与各种检测技术相结合,已经开发出了多种用于病原微生物检测的技术方法。相较于传统的病原微生物检测技术,微流控检测技术优势突出,具有操作人员技术要求不高、样本需求量少和自动化程度高等优点,适用于各种复杂环境下病原微生物的精准、快速检测。本文对微流控技术在病毒、细菌、真菌、衣原体及支原体等病原微生物的检测应用进行了综述,以期为病原微生物的检测提供研究思路,促进微流控技术在病原微生物检测中的发展,提高对疾病的预防和控制能力。

Rapid and accurate detection of pathogenic microorganisms is of great significance for epidemic prevention and control as well as the protection of people's lives and health.In recent years,researchers have developed a variety of technical methods for the detection of pathogenic microorganisms by reasonably designing microfluidic chips and combining microfluidic technology with various detection technologies.Compared with traditional pathogenic microorganism detection technology,microfluidic detection technology has outstanding advantages,i.e.,low technical requirements for operators,less sample demand and high degree of automation,and is suitable for accurate and rapid detection of pathogenic microorganisms in various complex environments.In this paper,the application of microfluidic technology in the detection of pathogenic microorganisms such as viruses,bacteria,fungi,chlamydia and mycoplasma was reviewed,aiming to provide research ideas for the detection of pathogenic microorganisms,promote the development of microfluidic technology in the detection of pathogenic microorganisms,and improve the prevention and control ability of diseases.