体外膜肺氧合患者出血高风险的防治策略

Prevention and treatment strategies for patients with extracorporeal membrane oxygenation at high risk of bleeding

体外膜肺氧合(ECMO)是治疗呼吸或心力衰竭的一种先进的生命支持方式。在ECMO支持期间,各种因素使得凝血功能受损,导致机体处于促凝和抗凝失衡的状态,因此增加了出血的发生率,同时对临床工作的开展也是一个巨大挑战。该文介绍了ECMO期间患者出血高风险相关的流行病学、病因及抗凝和监测,为临床提供参考。

Extracorporeal membrane oxygenation(ECMO)is an advanced life support modality for patients with respiratory or cardiac failure.During ECMO,various factors impair coagulation function,resulting in an imbalance between procoagulation and anticoagulation,thus increasing the incidence of bleeding and posing a significant challenge to the development of clinical work.In this article,the epidemiology,causes,anticoagulation and monitoring of high-risk bleeding during ECMO were reviewed,aiming to provide reference for clinical practice.