综合医院老年慢性胃炎患者合并焦虑抑郁情绪调查

Investigation on anxiety and depression in elderly patients with chronic gastritis in a general hospital

目的 调查安庆市某三甲综合医院老年慢性胃炎患者的焦虑抑郁情绪患病情况,探讨焦虑抑郁症状与一般人口学特征、幽门螺旋杆菌感染(Hp)等的相关性。方法 纳入105例老年慢性胃炎患者,经汉密尔顿焦虑量表(HAMA)及汉密尔顿抑郁量表17项(HAMD-17)评估患者焦虑、抑郁情绪,使用14C-尿素呼气试验检测幽门螺杆菌感染情况。结果 105例患者中伴有焦虑症状患者63例(60%),伴有抑郁症状患者63例(60%),焦虑症状与抑郁症状均同时存在,无焦虑抑郁症状的患者42例(40%);在伴有焦虑及抑郁的慢性胃炎患者中,性别和年龄均无统计学差异(P>0.05);但两者的受教育年限存在统计学差异(P<0.05);且伴有焦虑及抑郁患者的HP阳性率明显高于无焦虑抑郁患者,两者相比差异有统计学意义(P=0.012)。HAMA总分差异性有统计学意义,而HAMD-17总分接近显著差异(P=0.055)。结论 综合医院老年慢性胃炎患者中焦虑抑郁情绪的发生率较高,焦虑抑郁情绪与受教育年限、幽门螺旋杆菌感染有关,幽门螺杆菌感染与老年慢性胃炎患者焦虑症状存在相关性,以躯体化症状为主。

Objective To investigate the prevalence of anxiety and depressive symptoms in elderly patients with chronic gastritis in a tertiary general hospital in Anqing,and to explore the correlation between anxiety and depression symptoms and general demographic characteristics and Helicobacter pylori infection(Hp).Methods One hundred and five elderly patients with chronic gastritis were included and assessed for anxiety and depression by Hamilton Anxiety Inventory(HAMA)and 17-item Hamilton Rating Scale for Depression(HAMD-17).Mood,and H.pylori infection was detected using the 14C-urea breath test.Results Among 105 patients,63 patients(60%)had anxiety symptoms,63 patients(60%)had depressive symptoms,both anxiety and depressive symptoms existed together,and 42 patients(40%)had no anxiety and depressive symptoms;among patients with chronic gastritis with anxiety symptoms and depressive symptoms,there was no statistical difference in gender and age(P>0.05).However,there was a statistical difference in the number of years of education between them(P<0.05).There was a statistically significant difference(P<0.05),and the rate of HP positivity was significantly higher in patients with anxiety symptoms and depression than in patients without anxiety and depression,and the difference was statistically significant(P=0.012).The difference between the total HAMA score was statistically significant,while HAMD-17 total score approached significant difference(P=0.055).Conclusion The incidence of anxiety and depression was higher among elderly patients with chronic gastritis in general hospitals,and anxiety and depression were associated with years of education and H.pylori infection,and there was a correlation between H.pylori infection and anxiety symptoms in elderly patients with chronic gastritis,with somatization symptoms predominating.