药物治疗联合心理干预对肺结核伴抑郁情绪患者的疗效分析

Analysis of the Clinical Treatment Effect of Drug Therapy Combined with Psychological Intervention on Patients with Pulmonary Tuberculosis and Depression

目的探讨肺结核伴抑郁情绪患者应用药物治疗联合心理干预的临床效果。方法回顾性分析2021年1月~2022年12月期间北京市大兴区人民医院收治的100例肺结核伴抑郁情绪患者的临床资料,根据治疗方式的不同分组,给予心理治疗的50例纳入观察组,给予常规治疗的50例纳入对照组;对比两组汉密顿焦虑量表(HAMA)、17项汉密尔顿抑郁量表(HAMD-17)、知觉心理压力量表(CPSS)、用药依从性、生活质量评定问卷(GQOL1-74)。结果干预前,两组HAMA、HAMD评分对比(P>0.05),干预后,两组HAMA、HAMD评分均低于干预前(P<0.05),且观察组评分低于对照组(P<0.05);干预前,两组CPSS评分对比(P>0.05),干预后,两组CPSS评分均低于干预前(P<0.05),且观察组评分较对照组更低(P<0.05);观察组用药依从性明显高于对照组(P<0.05);干预前,两组GQOL1-74评分对比(P>0.05),干预后,两组GQOL1-74评分均高于治疗前(P<0.05),且观察组评分较对照组更高(P<0.05)。结论肺结核伴抑郁情绪患者在药物治疗的同时配合心理干预,可显著改善患者的焦虑抑郁负性情绪,提高用药依从性,提高生活质量,取得良好预后。

Objective To explore the clinical effect of drug therapy combined with psychological intervention on patients with pulmonary tuberculosis and depression.Methods The clinical data of 100 patients with depression caused by pulmonary tuberculosis admitted to Daxing District People's Hospital from January 2021 to December 2022 were retrospectively analyzed.According to the different groups of treatment methods,50 patients who received psychotherapy were included in the observation group,and 50 patients who did not receive psychotherapy were included in the control group;The Hamilton Anxiety Scale(HAMA),17 Hamilton Depression Scale(HAMD-17),Perceptual Psychological stress scale(CPSS),medication compliance,and quality of life assessment questionnaire(GQOL1-74)were compared between the two groups.Result Before intervention,the HAMA and HAMD scores of the two groups were compared(P>0.05).After intervention,the HAMA and HAMD scores of both groups were lower than before intervention(P<0.05),and the observation group's scores were lower than those of the control group(P<0.05).Before intervention,the CPSS scores of the two groups were compared(P>0.05).After intervention,both groups had lower CPSS scores than the control group(P<0.05),and the observation group had lower CPSS scores than the control group(P<0.05);The medication compliance of the observation group was significantly higher than that of the control group(P<0.05).Before intervention,the GQOL1-74 scores of the two groups were compared(P>0.05).After intervention,the GQOL1-74 scores of both groups were higher than those of the control group(P<0.05),and the observation group had a higher score than the control group(P<0.05).Conclusion Patients with pulmonary tuberculosis and depression can significantly improve their negative emotions of anxiety and depression,reduce stress,improve medication compliance,improve quality of life,and achieve a good prognosis by combining psychological intervention with medication treatment.