纤维支气管镜联合肺泡灌洗术在儿童肺炎合并肺不张中的治疗效果

Therapeutic Effect of Fiberoptic Bronchoscopy Combined with Alveolar Lavage in Children with Pneumonia Compli⁃cated with Atelectasis

目的:探究采用纤维支气管镜与肺泡灌洗联合治疗儿童肺炎合并肺不张的价值。方法:选取2021年1月—2022年12月常州市第一人民医院儿科收治的肺炎合并肺不张患儿120例为研究对象,随机分为观察组和对照组,各60例。对照组采用常规治疗,观察组采用纤维支气管镜联合肺泡灌洗术。比较两组治疗总有效率、症状消失时间、血清炎性指标水平及不良反应发生率。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P=0.004);观察组肺部哮鸣音、发热、肺部湿啰音、咳嗽症状消失时间短于对照组,差异有统计学意义(P<0.001);治疗后,两组降钙素原、红细胞沉降率、C反应蛋白水平均降低,观察组低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:采用纤维支气管镜与肺泡灌洗术联合治疗肺炎合并肺不张,可提升总有效率,缩短症状消失时间,降低炎性反应及不良反应发生率。

Objective:To explore the value of fiberoptic bronchoscopy combined with alveolar lavage in children with pneumonia complicated with atelectasis.Methods:A total of 120 children with pneumonia complicated with atelectasis were selected as the study objects in the Department of Pediatrics,Changzhou First People's Hospital from January 2021 to December 2022,and were randomly divided into observation group and control group,with 60 cases in each group.The control group received conventional treatment,and the observation group received fiberoptic bronchoscopy combined with alveolar lavage.The total effective rate,the time of symptom disappearance,the level of serum inflammatory indexes and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P=0.004);the disappearance time of wheezing,fever,moist rales and cough in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.001);after treatment,the levels of procalcitonin,erythrocyte sedimentation rate and C-reactive protein in both groups were decreased,and the observation group was lower than the control group,the difference was statistically significant(P<0.05);there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The combination of fiberoptic bronchoscopy and alveolar lavage in the treatment of pneumonia with atelectasis can improve the total effective rate,shorten the time of symptom disappearance,and reduce the incidence of inflammatory reaction and adverse reactions.