基于因子分析的纤维肌痛综合征中医证候分布特征研究

Research on TCM syndrome characteristics of fibromyalgia syndrome based on factor analysis

目的采用因子分析方法探讨纤维肌痛综合征的中医证候分布特征。方法采用回顾性研究方法,以102例纤维肌痛综合征患者为研究对象,从患者的临床病历中提取规范化症状,通过探索性因子分析总结纤维肌痛综合征患者症状、病位证素、病性证素及中医证候分布特点。结果根据各公因子病位证素、病性证素组合及各患者证素辨证结果,统计102例纤维肌痛综合征患者证候分布为:肝郁气滞证102例、阴(血)虚阳亢(扰神)证72例、寒湿痹阻证63例、脾肾阳(气)虚证22例、痰瘀阻络(心)证13例。结论纤维肌痛综合征的中医证候以肝郁气滞证最为常见,阴(血)虚阳亢(扰神)证、寒湿痹阻证、脾肾阳(气)虚证、痰瘀阻络(心)证也较为多见,各证可单独存在,亦可相兼出现。该证候特点反映出纤维肌痛综合征属因郁致痹,病位以肝为主涉及多脏,病性具有虚实夹杂、阴阳两伤的特点。

Objective To explore the characteristics of traditional of Chinese Medicine(TCM)syndromes of fibromyalgia syndrome by factor analysis.Methods A retrospective study was conducted on 102 patients with fibromyalgia syndrome.Standardized symptoms were extracted from the clinical medical records of the patients,and the distribution characteristics of symptoms,disease location syndrome elements,disease-related syndrome elements and TCM syndromes were summarized by exploratory factor analysis.Results According to the common factors of disease location syndrome,the combination of disease syndrome and the syndrome differentiation results of each patient,the syndrome distribution of 102 patients with fibromyalgia syndrome was summarized as:102 cases of liver depression and Qi stagnation syndrome,72 cases of Yin(blood)deficiency and Yang excess(disturbance of the mind)syndrome,63 cases of cold-damp obstruction syndrome,22 cases of spleen-kidney Yang(Qi)deficiency syndrome,and 13 cases of phlegm-blood stasis syndrome.Conclusion The most common TCM syndromes of fibromyalgia syndrome is liver stagnation and Qi stagnation syndrome,Yin(blood)deficiency and Yang excess(disturbance of the mind)syndrome,cold-damp obstruction syndrome,spleen-kidney Yang(Qi)deficiency,phlegm-blood stasis(heart)syndrome can exist alone or coexist.The characteristics of this syndrome reflect that fibromyalgia syndrome is a kind of Bizheng due to depression of Ganqi.The most common disease location syndrome elements is liver.The characteristic of disease-related syndrome elements is the mixture of deficiency and excess,and the deficiency of both Yin and Yang.