我国中老年人缺牙危险因素的Meta分析

Risk factors of tooth loss in middle-aged and elderly in China:a Meta-analysis

目的 系统评价我国中老年人发生缺牙的危险因素。方法 计算机检索CNKI、VIP、CBM、WanFang Data、PubMed、EMbase、Web of Science和The Cochrane Library,纳入关于我国中老年人缺牙危险因素的观察性研究,检索时限为各数据库建库至2023年3月。由2名研究者独立筛选文献、提取数据、评价文献质量,应用Stata 15.0进行Meta分析。结果 最终共纳入15项研究,缺牙检出对象为40400例。Meta分析结果显示,我国中老年人缺牙的发生与年龄(OR=1.68,95%CI 1.33~2.13)、女性(OR=1.23,95%CI 1.15~1.31)、居住在农村(OR=1.26,95%CI 1.18~1.35)、收入水平低(OR=1.17,95%CI 1.08~1.27)、吸烟(OR=1.09,95%CI 1.01~1.19)、蔬菜进食频率<2次/天(OR=1.18,95%CI 1.08~1.29)、高血压(OR=1.24,95%CI 1.03~1.50)、脑卒中(OR=1.51,95%CI 1.51~1.51)、心血管疾病(OR=1.28,95%CI 1.00~1.65)、牙线使用频率<1次/天(OR=2.32,95%CI 1.64~3.28)、认为刷牙时牙龈出血正常(OR=1.26,95%CI 1.09~1.46)有关。结论 年龄、女性、居住在农村、收入水平低、吸烟、蔬菜进食频率<2次/天、高血压、脑卒中、心血管疾病、牙线使用频率<1次/天、认为刷牙时牙龈出血正常是我国中老年人缺牙的危险因素。

Objective To systematically evaluate the risk factors of tooth loss in middle-aged and elderly in China.Methods Studies on the risk factors of tooth loss in middle-aged and elderly in China were searched in CNKI,VIP,CBM,WanFang Data,PubMed,EMbase,Web of Science and The Cochrane Library databases and the observational studies were included.The search time was from database inception to March 2023.Two researchers independently screened literature,extracted data and evaluated literature quality.The Meta-analysis was performed by Stata 15.0 software.Results A total of 15 studies were included finally,involving 40400 cases.Meta-analysis results showed that age(OR=1.68,95%CI 1.33~2.13),female(OR=1.23,95%CI 1.15~1.31),living in rural areas(OR=1.26,95%CI 1.18~1.35),low income(OR=1.17,95%CI 1.08~1.27),smoking(OR=1.09,95%CI 1.01~1.19),vegetables eating less than twice per day(OR=1.18,95%CI 1.08~1.29),hypertension(OR=1.24,95%CI 1.03~1.50),stroke(OR=1.51,95%CI 1.51~1.51),cardiovascular disease(OR=1.28,95%CI 1.00~1.65),teeth flossing less than once per day(OR=2.32,95%CI 1.64~3.28),considered normal gum bleeding during brushing(OR=1.26,95%CI 1.09~1.46)were risk factors of tooth loss in middle-aged and elderly in China.Conclusion Age,female,living in rural areas,low income,smoking,vegetables eating less than twice per day,hypertension,stroke,cardiovascular disease,teeth flossing less than once per day and considered normal gum bleeding during brushing were risk factors of tooth loss in middle-aged and elderly in China.