甘肃省临夏地区东乡族和汉族人群甲状腺结节的患病率及危险因素分析

Epidemiological investigation of thyroid nodules in Dongxiang and Han populations in Linxia area of Gansu province

目的调查甘肃省临夏地区东乡族和汉族人群甲状腺结节的患病情况,分析其危险因素。方法以甘肃省临夏地区18岁以上的东乡族和汉族常住居民为研究对象,收集人口学资料,行甲状腺B超及实验室检查,分为甲状腺结节组和非甲状腺结节组,Logistic回归分析其影响因素。结果共纳入1724名研究对象,甲状腺结节患病率为37.5%,其中东乡族为34.1%,汉族为39.7%(P<0.05);年龄≥50岁、肾小球滤过率降低、糖尿病、游离甲状腺素偏高为甲状腺结节的独立危险因素(P<0.05),而东乡族、男性、少食富碘食物是甲状腺结节的独立保护因素(P<0.05)。结论汉族人群患病率高于东乡族,针对危险因素,采取预防性措施,对减少甲状腺结节的发生发展至关重要。

Objective To investigate the prevalence and risk factors of thyroid nodules in Dongxiang and Han ethnic groups in Linxia area of Gansu province.Methods The permanent residents of two ethnic groups over 18 years old in Linxia of Gansu province were selected as the research objects.The demographic data,thyroid B-ultrasound and laboratory examination were performed.All subjects were divided into thyroid nodule group and non-thyroid nodule group,and the influencing factors were analyzed by Logistic regression.Results A total of 1724 subjects were included in the study.The prevalence of thyroid nodules was 37.5%,with 34.1%in Dongxiang ethic group and 39.7%in Han ethic group(P<0.05).Age≥50 years,decreased glomerular filtration rate,diabetes,and high free thyroxine were independent risk factors for thyroid nodules(P<0.05),while Dongxiang ethic group,male,and less iodine-rich food intake were independent protective factors for thyroid nodules(P<0.05).Conclusions The prevalence of thyroid nodules in Han nationality is higher than that in Dongxiang nationality.It is very important to take preventive measures against risk factors to reduce the occurrence and development of thyroid nodules.