特种芯光纤光镊技术研究进展

Advances in optical fiber tweezer technology based on hetero-core fiber

光纤光镊具有结构简单、操作灵活、尺寸小的特点,在生化分析、生命科学等领域有广泛应用。特殊纤芯结构的光纤探针在近场倏逝波光阱力、纤芯光束耦合传输、微流控技术交叉协同应用等方面具有天然优势,能实现细胞、亚细胞级微粒收集、输运等功能,可以显著提升微粒的三维捕获能力以及动态操纵水平。本文综述了不同纤芯结构光纤光镊的结构特点与应用技术研究进展,对特种芯光纤光镊系统中探针制备、激光光源、耦合方式等关键技术进行了梳理和对比,总结与展望了不同结构特种芯光纤在光纤光镊中的作用与发展。

Optical fiber tweezers are widely used in biochemical analysis,life sciences,and other fields due to their simple structure,flexible operation,and compact size.The hetero-core structure of the optical fiber probe possesses inherent advantages in near-field evanescent wave optical trapping force,core beam coupling transmission,and cross-synergistic application of microfluidic technology,which can realize the functions of cell and subcellular particle collection and transportation,and can significantly improve the three-dimensional particle trapping capability as well as dynamic manipulation level.In this paper,the structural characteristics and application technology research progress of optical fiber tweezers based on different core structures are reviewed.This paper sorts and compares key technologies,including probe preparation,laser source,and coupling mode,in hetero-core optical fiber tweezers systems.It also summarizes and provides a perspective on the role and development of hetero-core fibers with different structures in optical fiber tweezers.