规范化营养支持模式对非小细胞肺癌化疗患者的影响

Effect of standardized nutrition support model on chemotherapy patients with non-small cell lung cancer

目的:探讨规范化营养支持模式对非小细胞肺癌化疗患者的影响。方法:选取在2022年1~7月于同济大学附属上海市肺科医院接受化疗的100例非小细胞肺癌患者,根据随机数字法分为对照组(50例)和观察组(50例),对照组实施常规护理,观察组实施规范化营养支持模式,于入院当日、治疗完全结束前1 d比较两组患者营养风险发生情况、癌症病人生命质量得分等、治疗完全结束前1 d比较两组患者不良反应发生率。结果:入院当日,两组营养状态对比差异无统计学意义( P>0.05);治疗完全结束前1 d,与对照组比较,观察组不良反应发生率、营养风险发生情况、营养测定量表(PG-SGA)评分及骨髓抑制率明显降低,差异有统计学意义( P<0.05)。治疗完全结束前1 d观察组患者生命质量测定量表(QLQ-C30)评分高于对照组,差异有统计学意义( P<0.05)。 结论:规范化营养支持模式能够改善非小细胞肺癌化疗患者营养风险发生情况,降低不良反应的发生率,从而提升生命质量。

Objective To explore the effect of standardized nutritional support mode on chemotherapy patients with non-small cell lung cancer.Methods A total of 100 patients with non-small cell lung cancer who received chemotherapy in Shanghai Pulmonary Hospital Affiliated to Tongji University from January to July 2022 were selected and divided into control group(50 cases)and observation group(50 cases)according to the random number method.The control group was given routine nursing,while the observation group was given standardized nutritional support mode.On the day of admission and one day before the end of treatment,the incidence of nutritional risk and quality of life score of cancer patients were compared between the two groups,and the incidence of adverse reactions was compared between the two groups.Results On the day of admission,there was no statistically significant difference in nutritional status between the two groups(P>0.05).One day before the end of treatment,the incidence of adverse reactions,the incidence of nutritional risk,the score of Patient-Generated Subjective Global Assessment(PG-SGA)and the rate of bone marrow suppression in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).One day before the end of treatment,the score of the Quality of Life Questionnaire-Core 30(QLQ-C30)in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusions Standardized nutritional support mode can improve the nutritional risk of patients with non-small cell lung cancer undergoing chemotherapy,reduce the incidence of adverse reactions,so as to improve the quality of life.