摘要
Tongue-coating microbiome,as a part of oral microbiome,is an important part of commensal microbes in human body.Despite technical difficulties in gaining functional insights using metagenomic approaches due to high levels of host DNA contaminations,a number of diseases have been found to be closely related to the alteration of oral microbial communities,including periodontal and caries diseases,cardiovascular disease,diabetes,rheumatoid arthritis.
基金
supported by the Key Research Program of the Chinese Academy of Sciences under Grant KJZD-SW-L05 to Yixin Zeng and KJZD-SW-L05-04 to Hairong Chen
the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(Nos.ZYYCXTD-D-202001)to Jun Wang。
