摘要
Comprehensive Summary Enantioselective or enantioconvergent iron-catalyzed ring-closing C(sp^(3))-H aminations of N-aroyloxyurea through intermediate iron nitrene species provide chiral 2-imidazolidinones in up to 99%yield and with up to 95%ee(40 examples).This is a rare example in which sustainable iron catalysis is combined with C(sp^(3))-H amination and asymmetric catalysis.
基金
the European Research Council(ERC)under the European Union's Horizon 2020 research and innovation programme(grant agreement No.883212).