云南省男男性行为者rush等助性剂滥用及其相关因素

Prevalence and risk factors for abuse of chemsex such as rush poppers among men who have sex with men in Yunnan Province

目的了解云南省MSM中rush poppers、甲基苯丙胺和西地那非的滥用风险及相关危险因素。方法2022年11-12月对Blued软件云南用户及云南5个社会组织招募符合入选标准的MSM参与匿名线上问卷调查。结果回收有效问卷1002份,其中性角色为插入方262人(26.1%),接受方297人(29.6%),插入接受皆可390人(38.9%),自身认知不明53人(5.3%)。382人(38.1%)曾使用过rush poppers,17人(1.7%)报告曾使用过甲基苯丙胺,149人(14.9%)曾使用过西地那非,431(43.0%)人曾使用过上述三种物质中的其中一种;在同一次性行为中,101人(10.1%)同时使用rush poppers和西地那非。多因素Logistic回归发现,西地那非使用风险评分高是rush poppers使用风险的危险因素(OR=1.204,95%CI:1.065~1.360,P<0.01);物质使用负性态度是rush poppers使用风险的保护因素(OR=0.831,95%CI:0.772~0.956,P=0.01)。结论在云南省MSM中助性剂使用比例较高。西地那非使用是rush poppers使用的危险因素,且二者合用较为常见,将物质滥用干预专题作为减少伤害策略纳入MSM艾滋病精准防治刻不容缓。对物质使用的负性态度可以降低rush poppers使用风险,可作为物质使用心理行为干预的依据。

Objective To investigate the abuse risk and related risk factors of rush poppers,methamphetamine and sildenafil in men who have sex with men(MSM)in Yunnan Province.Methods An anonymous online questionnaire survey was carried out among MSM recruited from Blued APP and five social organizations in Yunnan,from November to December 2022.Results A total of 1002 valid questionnaires were collected,of which,262(26.1%)MSM only had insertive anal intercourse,297(29.6%)only had receptive anal intercourse,390(38.9%)had both insertive and receptive anal intercourse,and 53(5.3%)were uncertain about their sexual role.Among the MSM,382(38.1%)participants had used rush poppers,17(1.7%)had used methamphetamine,149(14.9%)had used sildenafil,and 431(43.0%)had used one of the three substances mentioned above.As per one time of sex intercourse,101(10.1%)participants had used both rush poppers and sildenafil.Multi-factor logistic regression analysis showed that,a high risk score for sildenafil abuse was a risk factor for rush poppers abuse(OR=1.204,95%CI:1.065-1.360,P<0.01),while negative attitudes towards substance abuse were protective factors(OR=0.831,95%CI:0.772-0.956,P=0.01).Conclusions A high proportion of substance use is found among MSM in Yunnan Province.Sildenafil use is a risk factor for rush poppers use,and the combined use of the two is more common.It's urgent to execute substance abuse interventions as a harm reduction strategy in the accurate prevention and treatment of HIV/AIDS among MSM.Negative attitudes towards substance abuse can reduce the risk of rush poppers abuse,and that can be used as evidence for psychological and behavioral interventions.