中医药治疗艾滋病领域研究的多维度可视化分析

Multi-dimensional visualization analysis on the prevention and treatment of AIDS with traditional Chinese medicine

目的运用引文空间分析原理分析近十年来中医药防治艾滋病领域的研究动态和前沿,为开展进一步研究提供一定参考。方法检索2011年1月1日至2020年12月31日由中国知识资源总库、万方数据库、中国科技核心期刊数据库和中国生物医学文献数据库收录的研究报道,利用CiteSpace和VOSviewer软件可视化分析近十年中医药防治艾滋病领域的研究报道。结果共纳入研究报道628篇,2011年发表文献最多达到88篇,之后文献发表数量呈总体下降趋势,刊文量最多的期刊为《中华中医药杂志》,发文量最多的机构和作者是河南中医药大学第一附属医院徐立然教授(46篇),研究主题主要集中在免疫功能重建(31.53%)、中医证候(8.63%)、病因病机(7.03%)、诊疗思路(6.43%)、相关皮肤病变(6.43%)等方面,形成了“#2中医证候”“#3辨证论治”“#5病因病机”“#6临床疗效”和“#7非药物疗法”5个聚类效果较高的关键词聚类。结论近十年来,中医药防治艾滋病领域已进入相对完善阶段,形成了较为稳定的研究团队和协作网络;但就艾滋病相关并发症和非艾滋病相关并发症的研究相对不足,在今后的研究当中应加强该领域研究以进一步发挥中西医协同治疗优势。

Objective To explore the trends and frontiers in the field of AIDS prevention and treatment with traditional Chinese medicine(TCM)in the past 10 years by using principles of citation spatial analysis,so as to provide a reference for the further research.Methods From January 1,2011 to December 31,2020,literatures from China National Knowledge Infrastructure,Wanfang Database,China Science and Technology Core Journal Database,and China Biology Medicine Disc were retrieved.The multi-dimensional visualization analysis was used to analyze literatures about prevention and treatment of AIDS with TCM by CiteSpace and VOSviewer software.Results A total of 628 reports were enrolled,of which,88(14.01%)were published in 2011,since then,the number of published reports showed a totally downward trend.The journal with highest publication volume was China Journal of Traditional Chinese Medicine and Pharmacy,and the institution and author with the highest publication volume was Prof.XU Liran from the First Affiliated Hospital of Henan University of TCM,respectively.The research topics mainly focus on immune reconstruction(31.53%),TCM syndrome(8.63%),etiology and pathogenesis(7.03%),syndrome differentiation(6.43%),and AIDS-defining skin lesions(6.43%).Five clusters with high clustering effects were formed,which were"#2 TCM syndrome""#3 syndrome differentiation""#5 etiology and pathogenesis""#6 clinical efficacy""#7 non-pharmacological therapy".Conclusions In the past 10 years,the research of TCM on AIDS prevention and treatment has been relatively mature,formed a more stable networks of researchers and collaboration.However,there are some limitations on studies of AIDS-complication and non-AIDS-complication,which are needed to be improved furtherly.