前交通动脉瘤形态学特征与破裂后出血体积的相关性研究

Correlation between Morphologic Features of Anterior Communicating Aneurysms and Bleeding Volume after Rupture

目的探讨前交通动脉瘤(anterior communicating artery aneurysms,AcomA)形态学特征与破裂后出血体积的相关性。方法收集我院AcomA破裂患者的临床资料,所有患者入院行头部CT及CTA检查,评估AcomA破裂后出血体积及动脉瘤形态参数,包括动脉瘤最大径线、动脉瘤高度、宽度、瘤颈宽度、尺寸比(size ratio,SR)、纵横比(aspect ratio,AR)、入射角度、动脉瘤角、载瘤动脉直径,长宽比。以出血体积为因变量,对上述参数进行spearman相关性检验,有统计学意义的参数再行多元线性回归分析。结果单因素分析中显著指标有年龄,高血压,动脉瘤宽度,入射角度以及AR(P<0.05);多元线性回归分析发现,影响出血体积的独立危险因素分别为年龄(P=0.001)和AR(P=0.018)。结论较大年龄及较大AR值可引起AcomA破裂后更大的出血量。

Objective To investigate the correlation between the morphological features of Anterior communicating artery aneurysms(AcomA)and the volume of bleeding after rupture.Methods To collect the clinical data of the patients with AcomA rupture in our hospital,All patients were admitted for brain CT and CTA examination to evaluate the bleeding volume and aneurysm morphology parameters after AcomA rupture,including the maximum diameter of aneurysm,aneurysm height,aneurysm width,neck width,size ratio(SR),the aspect ratio(AR),incidence angle,angle aneurysm,Width of parent artery,With the bleeding volume as the dependent variable,For the above parameters,Statistically significant repeat multiple linear regression analysis of the parameters.Results In the univariate analysis,the significant index age,hypertension,aneurysm width,angle of incidence,AR(P<0.05).Multiple linear regression analysis found that the independent risk factors affecting the bleeding volume were age(P=0.001)and AR(P=0.018),respectively.Conclusion Older age and larger AR value can cause greater bleeding volume after AcomA rupture.