多层螺旋CT增强在胃肠道间质瘤治疗前评估中的价值

The Value of Multi-slice Spiral CT Enhancement in Pretreatment Evaluation of Gastrointestinal Stromal Tumors

目的探讨多层螺旋CT增强在胃肠道间质瘤治疗前评估中的价值,为临床患者治疗方案的制定和疗效预测提供经验指导。方法采用回顾性研究方法,纳入赣榆区人民医院2019年6月-2022年12月37例经病理证实胃肠道间质瘤患者作为研究对象,所有患者均采用CT设备采用GE Optima64排螺旋CT扫描仪,进行平扫及三期增强扫描。将DICOM格式原始图像数据导入AW4.6工作站,运用MPR、VR、MIP等图像后技术进行观察病灶。重点检测增强扫描肿瘤内部强化方式及肿块实质的增强幅度等信息,通过统计学分析其评估价值。结果结果显示A组(n=12)平扫CT值40.11±8.47HU,动脉期、静脉期及延迟期CT值增强幅度分别为18.42±9.12HU、22.71±7.51HU、28.41±6.38HU;B组(n=13)平扫CT值38.12±6.42HU,动脉期、静脉期及延迟期CT值增强幅度分别为23.41±7.73HU、31.33±8.42HU、36.57±7.93HU;C组(n=12)平扫CT值37.37±7.78HU,动脉期、静脉期及延迟期CT值增强幅度分别为25.78±8.97HU、39.71±4.53HU、41.31±9.39HU。对比各组检测结果病变随着体积增大,危险程度增大,其增强各期强化幅度也随之增大,其中静脉期及延迟的增强幅度具有统计学意义(P<0.05)。结论胃肠道间质瘤治疗前影像学检查对于明确诊断和危险度分级评估以及GIST患者治疗方案制定和疗效预测具有重要的临床价值。

Objective Exploring the value of multi-slice spiral CT enhancement in pre treatment evaluation of gastrointestinal stromal tumors,providing empirical guidance for the formulation of clinical patient treatment plans and efficacy prediction.Methods Using a retrospective study method,37 patients with pathologically confirmed gastrointestinal stromal tumors from Ganyu District People's Hospital from June 2019 to December 2022 were included as the study subjects.All patients were scanned using a GE Optima 64 row spiral CT scanner using CT equipment for plain and three phase enhanced scans.Import the raw image data in DICOM format into the AW4.6 workstation,and use postimage techniques such as MPR,VR,and MIP to observe the lesion.Focus on detecting the internal enhancement mode of the tumor and the enhancement amplitude of the tumor parenchyma in enhanced scanning,and evaluate its value through statistical analysis.Results The results showed that the CT values of group A(n=12)were 40.11±8.47 HU on plain scan,and the enhancement amplitudes of CT values in arterial,venous,and delayed phases were 18.42±9.12 HU,22.71±7.51 HU,and 28.41±6.38 HU,respectively;Group B(n=13)had a plain CT value of 38.12±6.42HU,and an enhanced amplitude of 23.41±7.73HU,31.33±8.42HU,and 36.57±7.93HU in arterial,venous,and delayed phases,respectively;The CT value of group C(n=12)was 37.37±7.78 HU on plain scan,and the enhancement amplitude of CT values in arterial,venous,and delayed phases was 25.78±8.97 HU,39.71±4.53 HU,and 41.31±9.39 HU,respectively.Comparing the detection results of each group,as the volume of the lesion increases,the risk level increases,and the enhancement amplitude of each phase also increases.Among them,the enhancement amplitude of the venous phase and delayed phase is statistically significant(P<0.05).Conclusion The preoperative imaging examination of gastrointestinal stromal tumors has important clinical value for clear diagnosis and risk assessment,as well as for the formulation of treatment plans and efficacy prediction in GIST patients.