病理性近视新生血管导致黄斑出血的治疗研究进展

Research Progress on Treatment of Macular Hemorrhage due to Neovascularization in Pathological Myopia

从病理性近视新生血管导致黄斑出血的发病机制出发,总结中医治疗该病的研究现状。指出肝血不通、肾精衰弱和脾胃运化不良会影响黄斑的功能。肝肾阴虚证选驻景丸加减补益肝肾;加味知柏地黄丸补肾健脾、清热凉血;脾气虚弱证选加味八珍丸健脾益气;肝郁化火证用丹栀逍遥散加味疏肝解郁、泻火明目。当患者出血时间长或量较多时,通过驻景丸、点睛复明汤、桂枝茯苓丸合归脾汤、生蒲黄汤加减专方治疗以减少出血,提高患者视力。根据患者的病情缓急选择中医治疗或中西医结合治疗,能有效预防并减少病理性近视新生血管引起黄斑出血导致的并发症,在提高视功能及改善全身症状方面具有一定优势。参考文献33篇。

Based on the pathogenesis of macular hemorrhage due to neovascularization in pathological myopia,this paper summarizes the research status of traditional Chinese medicine in treating the disease.It is pointed out that obstruction of liver blood,deficiency of kidney essence and poor transportation and transformation of spleen and stomach will affect the function of the macula.For yin deficiency of liver and kidney syndrome,the modified Zhujing Pill(驻景丸)is selected to nourish liver and kidney.Jiawei Zhibo Dihuang Pill(加味知柏地黄丸)is used to tonify kidney and invigorate spleen,clear heat and cool blood.In cases of spleen qi deficiency,Jiawei Bazhen Pill(加味八珍丸)is selected to invigorate spleen and replenish qi.For liver depression transforming into fire syndrome,the modified Danzhi Xiaoyao Power(丹栀逍遥散)is used to soothe liver and relieve depression,clear heat and improve vision.In cases where bleeding persists or is excessive,specific formulas such as Zhujing Pill,Dianjing Fuming Decoction(点睛复明汤),Guizhi Fuling Pill(桂枝茯苓丸)in combination with Guipi Decoction(归脾汤)and modified Shengpuhuang Decoction(生蒲黄汤)are used to reduce bleeding and enhance the patient’s eyesight.Depending on the urgency and severity of the patient’s condition,traditional Chinese medicine treatment or a combination of traditional Chinese and western medicine can be selected.This approach can effectively prevent and reduce complications caused by macular hemorrhage due to neovascularization in pathological myopia which has certain advantages in improving visual function and alleviating systemic symptoms.There are 33 references in total.