信息化血糖管理在胰十二指肠切除患者中的应用

Application of Informatized Blood Glucose Management in Patients with Pancreaticoduodenectomy

目的探讨信息化血糖管理在胰十二指肠切除患者中的应用效果。方法选取64例胰十二指肠切除患者按随机数字表法分为观察组与对照组各32例,观察组采用实时动态血糖监测系统,按血糖调控方案调整静脉泵注胰岛素用量;对照组采用传统血糖监测方法,按比例通过中和葡萄糖静脉输注胰岛素。对比2组患者术后1~3 d、4~6 d血糖平均值及并发症发病率、平均住院日。结果观察组术后1~3 d、4~6 d血糖平均值分别为(5.8±0.4)mmol·L^(-1)、(5.4±0.5)mmol·L^(-1),对照组分别为(7.8±1.6)mmol·L^(-1)、(7.3±1.5)mmol·L^(-1),组间差异均有统计学意义(P<0.05);观察组与对照组术后并发症总体发病率(9.4%vs 34.4%)及平均住院日[(14.6±3.2)d vs(16.5±3.7)d]比较差异均有统计学意义(P<0.05)。结论实时动态血糖监测对胰十二指肠切除患者进行精细信息化血糖管理,可使血糖控制在理想水平,有利于减少术后并发症,缩短平均住院日。

Objective To investigate the application effect of informatized blood glucose management in patients with pancreaticoduodenectomy.Methods A total of 64 patients with pancreaticoduodenectomy were enrolled and randomly divided into the observation group and the control group,with 32 cases in each group.Patients in the observation group adopted a real-time dynamic blood glucose monitoring system,and adjusted the dosage of intravenous insulin injection according to the blood glucose control plan;Patients in the control group adopted the traditional blood glucose monitoring method and received proportional intravenous insulin infusion through neutralizing glucose.The average blood glucose in postoperative 1~3 d and 4~6 d,the overall incidence of complications,and the average hospital stay were compared between the two groups.Results The average blood glucose in postoperative 1~3 d,4~6 d were(5.8±0.4)mmol·L^(-1),(5.40.5)mmol·L^(-1)in the observation group,and(7.8±1.6)mmol·L^(-1),(7.3±1.5)mmol·L^(-1)in the control group,respectively,with statistically significant differences between the groups(P<0.05).The postoperative overall incidence of complications and average hospital stay were 9.4%,(14.6±3.2)d in the observation group,and 34.4%,(16.5±3.7)d in the control group.There were significant difference between the two groups(P<0.05).Conclusion Real time dynamic blood glucose monitoring provides precise information-based blood glucose management for patients undergoing pancreaticoduodenectomy,which can control blood glucose at an ideal level,reduce postoperative complications,and shorten the average hospital stay.