临床药师参与糖尿病足患者治疗的效果评价

Effect evaluation of the clinical pharmacists participating in the treatment of patients with diabetic foot

目的 评估临床药师参与住院糖尿病足患者治疗对抗菌药物管理指标和卫生经济学指标的影响。方法 选择2017年4月至2017年9月在空军特色医学中心内分泌科住院治疗的wagner4级糖尿病足患者40例为对照组,2019年4月至2019年9月在内分泌科住院治疗的wagner4级糖尿病足患者40例为干预组,对照组临床药师未参与患者药物治疗监护,干预组临床药师参与药物治疗,开展抗菌药物管理、药物重整、药学监护和用药教育,比较两组的疗效、抗菌药物管理指标(抗菌药物使用强度、特殊级抗菌药物使用率)和卫生经济学指标(药费、住院费用)。结果 两组患者疗效相当,临床药师干预组抗菌药物使用强度和特殊级抗菌药物使用率显著低于对照组(P<0.01),同时药费和住院费用也显著低于对照组(P<0.01)。结论 临床药师参与糖尿病足患者的药物治疗可以优化抗菌药物管理指标和卫生经济学指标,促进合理用药,节省医疗费用。

Objective To evaluate the effect of clinical pharmacists participating in the treatment of hospitalized patients with diabetic foot by antibiotics management index and health economics index.Methods 40 hospitalized patients with diabetic foot of Wagner Grade 4 in the Endocrine Department of Air Force Medical Center from April to September 2017 were selected as control group,and 40 hospitalized patients with diabetic foot of Wagner Grade 4 in the Endocrine Department from April to September 2019 were selected as interventional group.No clinical pharmacists were involved in drug treatment of patients in the control group,while the clinical pharmacists in the interventional group participated in drug treatment,and implemented antimicrobial stewardship,medication reconciliation,pharmaceutical care and medication education.Antibiotics management indexes(use intensity of antibiotics,use rate of special class antibiotics)and health economics indexes(medicine expenses,hospitalization expenses)of the two groups were compared.Results The efficacy of the two groups was similar.The use intensity of antibiotics and use rate of special class antibiotics of the interventional group in which clinical pharmacists participated were significantly lower than the control group(P<0.01),so were the medicine expenses and hospitalization expenses(P<0.01).Conclusion Clinical pharmacists participating in the treatment of hospitalized patients with diabetic foot could reduce antibiotics administration index and health economics index,promote rational medicine use and save medical expenses.