鼻腔雾化吸入糖皮质激素治疗儿童上气道咳嗽综合征的临床效果

Clinical effect of nasal aerosol inhalation of glucocorticoid in the treatment of upper airway cough syndrome in children

目的探讨鼻腔雾化吸入糖皮质激素治疗儿童上气道咳嗽综合征的临床效果。方法选取2021年12月至2022年12月于北京京都儿童医院接受治疗的86例上气道咳嗽综合征患儿,按照不同治疗方法分为对照组(46例)和观察组(40例)。对照组采用糖皮质激素鼻喷雾剂治疗,观察组采用鼻腔雾化吸入糖皮质激素治疗。比较两组临床症状控制时间、治疗效果及不良反应总发生率。结果观察组咳嗽、鼻塞流涕控制时间均短于对照组(P<0.05)。观察组总有效率高于对照组(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论鼻腔雾化吸入糖皮质激素治疗儿童上气道咳嗽综合征的临床效果较好,有利于控制临床症状,临床可推广应用。

Objective To investigate the clinical effect of nasal aerosol inhalation of glucocorticoid in the treatment of upper airway cough syndrome in children.Methods A total of 86 children with upper airway cough syndrome treated in Beijing Jingdu Children’s Hospital from December 2021 to December 2022 were selected and divided into the control group(46 cases)and the observation group(40 cases)according to different treatment methods.The control group was treated with glucocorticoid nasal spray,and the observation group was treated with nasal aerosol inhalation of glucocorticoid.The control time of clinical symptoms,therapeutic effect and total incidence of adverse reactions were compared between the two groups.Results The control time of cough,nasal obstruction and runny nose in the observation group was shorter than that in the control group(P<0.05).The total effective rate of the observation group was higher than that of the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Nasal aerosol inhalation of glucocorticoid in the treatment of children with upper airway cough syndrome has good clinical effect,which is beneficial to control clinical symptoms,and can be popularized in clinical application.