未足月胎膜早破的管理:争议与挑战

Management of preterm premature rupture of membranes: controversies and challenges

未足月胎膜早破(preterm premature rupture of membranes,PPROM)因发病率不低,且与早产、母儿感染、新生儿呼吸疾病等并发症有关,一直是产科临床研究的热点问题。虽然近年来PPROM管理在不断更新和完善,但一些争议和挑战仍然存在。如PPROM诊断后,是否需要卧床休息?是终止妊娠还是期待治疗?如何使用各种治疗药物才能起到最佳的治疗效果?本文将根据近年来的最新证据对目前存在的争议与挑战进行详细阐述。

Preterm premature rupture of membranes(PPROM)is always an important issue in obstetric clinical studies for its high incidence and association with maternal and neonatal morbidity,such as preterm birth,infection,respiratory disease,etc.Although the management of PPROM has been updated and improved in recent years,some controversies and challenges still exist.Are PPROM women required for bed rest?Which is better for PPROM women,labor induction or expectant treatment?How to select various medications to achieve the best effect for PPROM women?Based on the newest evidence in recent years,this paper elaborates on the above issues in detail.