Tuebingen库欣病生活质量量表的汉化及信效度检验

Chinesization and reliability and validity test of Tuebingen Cushing′s Disease Quality of Life Inventory

目的:汉化Tuebingen库欣病生活质量量表(Tuebingen CD-25)并检验其信效度。方法:参照世界卫生组织跨文化研究指南和Brislin翻译模型将Tuebingen CD-25翻译为中文,通过专家咨询、认知性访谈和预调查形成中文版Tubingen CD-25。采用便利抽样法,于2022年4月—2023年3月选取上海市某三级甲等医院的203例库欣病病人作为研究对象以检验中文版Tubingen CD-25的信度和效度。结果:中文版Tuebingen CD-25包含社会交往、情绪感受、饮食行为、躯体活动限制、性生活、认知6个维度,共25个条目。量表水平的内容效度指数为0.97,条目水平的内容效度指数为0.83~1.00。探索性因子分析提取的6个公因子累积方差贡献率为69.541%。中文版Tuebingen CD-25总分与简明健康状况问卷总分呈负相关,相关系数为-0.731(P<0.001)。量表总体的Cronbach′s α系数为0.919,重测信度为0.919(P<0.01)。结论:中文版Tuebingen CD-25具有良好的信效度,是适用于我国库欣病病人的特异性生活质量评估工具。

Objective:To translate Tuebingen Cushing′s Disease Quality of Life Inventory(Tuebingen CD⁃25)into Chinese,and test its reliability and validity.Methods:Referring to the World Health Organization′s cross⁃cultural research guidelines and the Brislin translation model,Tuebingen CD⁃25 was translated into Chinese.The Chinese version of Tuebingen CD⁃25 was formed through expert consultation,cognitive interviews,and pre⁃surveys.A total of 203 patients with Cushing′s disease from a tertiary grade A hospital in Shanghai was selected as subjects from April 2022 to March 2023 by convenience sampling method to test reliability and validity of the Chinese version of Tuebingen CD⁃25.Results:The Chinese version of Tuebingen CD⁃25 included 6 dimensions(social interaction,emotional feelings,dietary behavior,physical activity limitations,sexual activity,cognition),with a total of 25 items.the scale⁃level CVI was 0.97,and the item⁃level CVI ranged from 0.83 to 1.00.The cumulative variance contribution rate of the 6 common factors extracted through exploratory factor analysis was 69.541%.The total score of the Chinese version of Tuebingen CD⁃25 was negatively correlated with the total score of The 36⁃Item Short Form Health Survey,with correlation coefficient of-0.731(P<0.001).Cronbach′sαcoefficient of the scale population was 0.919,and the retest reliability was 0.919(P<0.01).Conclusions:The Chinese version of Tuebingen CD⁃25 has good reliability and validity.It is a specific quality of life assessment tool suitable for patients with Cushing′s disease in China.