青年结肠腺癌患者肿瘤部位及其类型与生存状态分析

Tumor sites and types in young patients with colon adenocarcinoma and survival status analysis

目的探讨不同原发部位的青年结肠腺癌患者出院后健康状况及生存状态。方法回顾性分析285例青年结肠腺癌患者的临床资料,随机选取同期的285例老年结肠腺癌患者临床资料进行对比,对其不同部位结肠腺癌患者及其出院后健康状况和生存状态进行分析。结果青年结肠腺癌患者中,男154例,女131例,升结肠、横结肠、降结肠、乙状结肠发病率分别为25.3%、11.6%、18.9%、44.2%,主要为Ⅲ、Ⅳ期病例(32.0%、47.7%)和中、低分化病例(40.3%、37.9%),出院后51.2%患者能行为自理,其中横结肠腺癌患者发病率最低(11.6%),行为自理比率最高(42.4%),5年生存率最高(75.7%);乙状结肠腺癌发病率最高(44.2%),行为非自理比率较高(40.5%),5年生存率最低(69.0%)。结论不同原发部位的结肠腺癌患者院外健康状况及生存状态存在差异,青年结肠腺癌患者以乙状结肠腺癌多见,横结肠腺癌发病率最低;出院后行为自理者以横结肠腺癌患者最多。

Objective To investigate the health status and survival status of young patients with colon adenocarcinoma of different primary sites after discharge.Methods The clinical data of 285 young patients with colon adenocarcinoma were retrospectively analyzed.At the same time,the clinical data of 285 elderly patients with colon adenocarcinoma were compared with those randomly selected.The health status and survival status of the patients with colon adenocarcinoma in different sites and after discharge were analyzed.Results Among the young colon adenocarcinoma patients,there were 154 males and 131 females,and the incidences of ascending colon,transverse colon,descending colon and sigmoid colon were 25.3%,11.6%,18.9%and 44.2%.After discharge,51.2%of the patients had behavioral self-care,and the incidence of transverse colon adenocarcinoma was lowest(11.6%).The rate of behavioral self-care was the highest(42.4%),and the 5-year survival rate was the highest(75.7%).The incidence of sigmoid adenocarcinoma was the highest(44.2%),while the rate of behavioral self-care was higher(40.5%).The 5-year survival rate was the lowest(69.0%).Conclusion The out-of-hospital health status and survival status of colon adenocarcinoma patients are different in different primary sites.Sigmoid adenocarcinoma is the most common in young colon adenocarcinoma patients,and transverse colon adenocarcinoma has the lowest incidence.The patients with transverse colon adenocarcinoma are the most self-care after discharge.