高分辨质谱在农药残留检测中的应用

Application of High-resolution Mass Spectrometry in Pesticide Residue Detection

高分辨质谱是一种将样品经色谱和部分质谱分离与离子化、再经质谱检测器得到图谱并实现对已知或未知物质进行定性、定量分析的技术。因其高通量、分析速度快、灵敏度高、分辨率高等特点,近年被广泛运用于农药残留检测中。本文综述了近年高分辨质谱技术在农药残留检测领域中的研究进展,对高分辨质谱应用于农药残留检测的相关文献进行了分析,总结了飞行时间质谱(TOF)和静电场轨道阱质谱(Orbitrap)及其与其他检测方法联用(如气相色谱、液相色谱等)检测各类食品中农药残留的应用情况,并对其未来发展方向进行了展望,旨在为今后相关人员开展农药残留检测提供参考。

High-resolution mass spectrometry is a qualitative and quantitative analysis technology for known or unknown substances,which separated and ionized samples by chromatography and partial mass spectrometry,and then obtained chromatogram by a mass spectrometry detector.Because of the characteristics of high-throughput,fast analysis speed,high sensitivity and high-resolution,it has been widely used in pesticide residue detection in recent years.This paper reviewed the research progress on high-resolution mass spectrometry in the field of pesticide residues detection in recent years,analyzed the relevant literature on the application of high-resolution mass spectrometry in pesticide residue detection,and summarized the applications of time-of-flight mass spectrometry(TOF),electrostatic field orbital trap mass spectrometry(Orbitrap),and their combination with other detection methods(such as gas chromatography,liquid chromatography,etc.)in pesticide residue detection in various types of food.The prospect of future development direc-tion of high-resolution mass spectrometry was discussed to provide references for relevant personnel to detect pesticide residues in the future.