摘要
目的探讨青年大脑中动脉(middle cerebral artery,MCA)狭窄的高分辨率磁共振血管壁成像(high resolution magnetic resonance vessel wall imaging,HRMR-VWI)的影像表现,比较不同病因所致的青年MCA狭窄的临床危险因素及影像特征。方法回顾性收集2017—2019年接受HRMR-VWI检查并符合入组标准的青年(16~45岁)患者76例。记录患者临床资料,分析其HRMR-VWI影像表现。根据出院诊断将患者分为动脉粥样硬化(atherosclerosis,AS)组及非AS组,比较不同病因所致MCA狭窄的影像特征,比较≤35岁患者与>35~45岁患者的临床危险因素及影像特征。结果AS组49例[(35.76±5.29)岁,女5例],非AS组27例[(31.07±7.47)岁,女16例]。AS组女性比例低于非AS组(10.2%vs.59.3%,P<0.001),吸烟患者比例(83.7%vs.14.8%,P<0.001)、高脂血症患者比例(63.3%vs.18.5%,P<0.001)高于非AS组,差异有统计学意义。HRMR-VWI显示AS组多为偏心性管壁增厚(44/49,89.8%),非AS组多为同心性管壁增厚(23/27,85.2%),组间差异存在统计学意义(P<0.001),且两组间最大管壁厚度差异存在统计学意义(P<0.001)。>35~45岁的患者高血压比例高于≤35岁患者(54.3%vs.29.3%,P=0.027)。结论AS仍为中国青年人群MCA狭窄的常见病因;非动脉粥样硬化性疾病的青年女性比例更高。AS与非动脉粥样硬化性MCA狭窄的影像特征方面,管壁增厚方式及最大管壁厚度可以作为鉴别诊断的依据。
Objective To investigate the imaging features of middle cerebral artery(MCA)stenosis in young patients on high resolution magnetic resonance vessel wall imaging(HRMR-VWI),and compare the clinical risk factors and imaging features of MCA stenosis in young patients with different causes.Methods Totals of 76 patients(16≤age≤45 years)with MCA stenosis who had HRMR-VWI examination and met the inclusion criteria between 2017 and 2019 were collected retrospectively.The clinical data of the patients were recorded,and the HRMR-VWI findings were analyzed.The patients were divided into atherosclerosis(AS)group and non-AS group based on their discharge diagnosis.To compare the imaging features of MCA stenosis caused by different causes in young patients,the clinical risk factors and imaging features were compared between the patients aged≤35 years and the patients aged over 35 years.
作者
梁佳
康慧斌
李葆青
隋滨滨
LIANG Jia;KANG Huibin;LI Baoqing;SUI Binbin(Department of Radiology,Shijingshan Teaching Hospital of Capital Medical University,Beijing Shijingshan Hospital,Capital Medical University,Beijing 100040,China;Department of Neurosurgery,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Neuroimaging Center,Beijing Tiantan Hospital,Capital Medical University,China National Clinical Research Center for Neurological Diseases,Beijing 100070,China)
出处
《中国卒中杂志》
2023年第11期1255-1261,共7页
Chinese Journal of Stroke
基金
国家自然科学基金项目(62271061)。
关键词
磁共振成像
高分辨率磁共振血管壁成像
大脑中动脉
动脉粥样硬化
血管炎
Magnetic resonance imaging
High resolution magnetic resonance vessel wall imaging
Middle cerebral artery
Atherosclerosis
Vasculitis