转化化学:医学驱动的化学前沿研究

Translational Chemistry:Frontier Chemical Research Driven by Medicine

本文围绕医学与化学的前沿交叉研究,基于第288期双清论坛的研讨内容,提出通过临床医学的问题和场景来启发化学的前沿研究,进而通过分子科学的创新推动医学问题的解决。这一研究思路有望推动“转化化学”的快速发展,促进化学和医学两个学科的协同创新。同时,本文还凝练了该领域的主要研究方向和若干关键科学问题,指出面临的技术瓶颈,思考未来5~10年的发展目标和资助重点。

tBased on the 288th Shuangqing Forum,this paper focuses on the frontier researches at the interface of medicine and chemistry,and then proposes the use of problems raised by clinical scenarios to inspire cutting-edge researches in chemistry,in which the innovation of molecular science could be promoted and will,in turn,provide fundamental solutions for the clinical problems.This process is expected to promote the interdisciplinary research of“translational chemistry”,and then accelerate the collaborative innovation of the two disciplines of chemistry and medicine.Furthermore,we summarize potential directions and key scientific issues of translational chemistry,and also point out existing technical barriers to be overwhelmed.Finally,goals as well as priorities of the funding policy in this field are suggested for the next 5-1o years.