体外受精-胚胎移植患者配偶心理状况调查及影响因素分析

Investigation of the psychological status and its influence factors analysis of the spouses of patients with in vitro fertilization-embryo transfer

目的:调查体外受精-胚胎移植(IVF-ET)助孕患者配偶的心理状况,探究有关影响因素。方法:选取2021年10月-2022年10月在本院行IVF-ET助孕的186例患者配偶,在治疗周期第1天应用抑郁自评量表(SDS)、焦虑自评量表(SAS)调查抑郁、焦虑状况。收集一般资料、应对方式、心理弹性情况,采用logistic多因素回归分析抑郁、焦虑影响因素。结果:调查的186例中,存在抑郁症状45例(24.2%),存在焦虑症状38例(20.4%)。单因素分析显示,年龄、既往治疗时间、对IVF-ET认知、消极应对评分、积极应对评分、CD-RISC-10评分与抑郁发生有关;家庭人均月收入、既往治疗时间、对IVF-ET认知、消极应对评分、积极应对评分、CD-RISC-10评分与焦虑有关(均P<0.05)。多因素分析显示,既往治疗时间长、消极应对评分高均为抑郁发生的独立危险因素,对IVF-ET更了解、积极应对评分高、CD-RISC-10评分高均为抑郁发生的独立保护因素;家庭人均月收入高对IVF-ET更了解、积极应对评分高、CD-RISC-10评分高均为焦虑的独立保护因素,既往治疗时间长、消极应对评分高均为焦虑的独立危险因素。结论:IVF-ET助孕患者配偶抑郁、焦虑症状发生率较高,影响因素多样,临床可依据影响因素采取针对性干预。

Objective:To investigate the psychological status of the spouses of patients with the assisted reproduction by in vitro fertilization-embryo transfer(IVF-ET),and to explore the related influencing factors of the psychological status of the spouse of the patients.Methods:The spouses of 186 patients who had received assisted reproduction by IVF-ET were selected in the study from Oetober 2021 to October 2022.On the first day of the treatment cycle of the patients,self-rating depression scale(SDS)and self-rating anxiety scale(SAS)were used to investigate the depression and anxiety of the patients'spouses.The general information,the coping style,and the mental resilience of the patients spouse were collected.Logistic multi factor regression analysis was used to explore the influencing factors of the depression and anxiety of the patients spouse.Results:Of 186 patients'spouse,45(24.2%)cases had depression symptoms and 38(20.4%)cases had anxiety symptoms.Univariate analysis showed that the age,the previous treatment time of the patients,the cognition for IVF-ET,the negative coping score,the positive coping score,and the CD-RISC-10 score of the patients'spouses were related to their depression(P<0.05).The family average monthly income,the previous treatment time of the patients,the cognition for IVF-ET,the negative coping score,the positive coping score,and the CD-RISC-10 score of the patients'spouses were related to their anxiety(all P<0.05).Multivariate analysis showed that the long duration of the previous treatment of the patients and the high negative coping score of the patients'spouses were the independent risk factors of their depression.The better understanding of IVF-ET,and the high positive coping and high CD-RISC-10 scores of the patients'spouses were the independent protective factors of their depression.The high family average monthly income,the better understanding of IVF-ET,and the high positive coping and CD-RISC-10 scores of the patients'spouse were the independent protective factors of their anxiety.The long duration of the previous treatment of the patients and the high negative coping score of the patients'spouses were the independent risk protective factors of their anxiety.Conclusion:The spouses of the patients with assisted reproduction by IVF-ET have the higher incidences of depression and anxiety symptoms,and their influencing factors are diverse.So the clinical intervention should be targeted conduction according to these influencing factors.