腹膜透析相关动物模型的研究进展

Research progresses in peritoneal dialysis related animal models

腹膜透析动物模型为人类改善腹膜透析治疗提供了重要的参考和依据,虽然到人类临床应用之前,仍需进行更多的研究和验证。目前研究者们已经使用小鼠、大鼠、兔子、猪等动物建立了腹膜透析动物模型。从新型透析液的研发,到腹膜炎、腹膜纤维化等并发症的治疗和机制研究,腹膜透析动物模型都发挥了重要的价值。

Peritoneal dialysis(PD)related animal models provide important references for improving PD treatment in humans,despite the fact that animal results have to be further studied before they can be used clinically.Currently,PD related models have been established in mice,rats,rabbits,pigs and other animals.These animal models offer valuable information about the mechanisms of PD complications such as peritonitis and peritoneal fibrosis,and also about the development of new dialysates.