摘要
花粉-食物过敏综合征(PFAS)是主要由IgE介导的一种特殊的食物过敏类型,一般发生在花粉过敏患者,由与花粉具有交叉致敏的植物源性食物诱发,部分可发生严重过敏反应。脂质转移蛋白(LTP)是与严重过敏反应相关的致敏蛋白组分。目前国内PFAS并未被充分认识和正确诊断,由其发生的严重过敏反应风险可能被低估。本文对PFAS现有的流行病学、临床特征、交叉致敏组分、诊断和治疗等研究进展进行综述,旨在进一步推进PFAS的识别和精准诊断,预防严重过敏反应发生。
Pollen-food allergy syndrome(PFAS)isonekindof special types of food allergy mainly mediated by immunoglobulin E(IgE),which usually occurs among patients with pollen allergyand is caused by food derivedfrom plant due tocross-reactivity with pollen.PFAS can cause anaphylaxis in some cases.Lipid transfer protein(LTP)is one kind of allergenic components correlated with anaphylaxis.At present,PFAS is not fully recognized and correctly diagnosed in Chinaand the potential risk of anaphylaxis caused by PFAS might be under-estimated.Literatures regarding epidemiology,clinical patterns,cross-reactive allergens,diagnosis and treatment of PFAS were summarized in this review,in order to further promote the identification and accurate diagnosis of PFAS and to prevent the occurrence of anaphylaxis.
作者
姜楠楠
向莉
JIANG Nan-nan;XIANG Li(Key Laboratory of Major Diseases in Children,Ministry of Education,Department of Allergy,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing 100045,China)
出处
《中华临床免疫和变态反应杂志》
CAS
2023年第5期455-463,共9页
Chinese Journal of Allergy & Clinical Immunology
基金
国家呼吸系统疾病临床医学研究中心“呼吸专项”(HXZX-20210203,HXZX-20210204,HXZX-202107)
北京市研究型病房建设示范单位项目(BCRW202101)。
