糖尿病患者临床参数与前列腺体积的相关性分析

Correlation Analysis of Clinical Parameters and Prostate Volume in Diabetic Patients

目的探讨糖尿病患者年龄、血液炎症参数与前列腺体积的相关性,以期对良性前列腺增生预防和治疗提供价值。方法回顾性分析2021年2月~2022年6月在哈尔滨医科大学附属第一医院检验报告处理系统上查询诊断为糖尿病且在内分泌科住院的496例患者。以前列腺体积是否≥30ml进行分组,将其分为糖尿病不伴有前列腺体积增大组(n=406)和糖尿病伴有前列腺体积增大组(n=90)。收集患者的年龄、血液炎性相关指标、尿液白细胞数,患者经腹部B超检查前列腺的前后径、上下径和左右径。结果两组间年龄、淋巴细胞、单核细胞、血小板、前列腺体积和单核细胞与淋巴细胞比值(monocyte-to-lymphocyte ratio,MLR)比较,差异均有统计学意义(P<0.05)。将糖尿病伴有前列腺体积增大组的临床参数进行相关性分析时,年龄、血小板与淋巴细胞比值(platelet-to-lymphocyte ratio,PLR)和MLR与前列腺体积呈正相关(r分别为0.24、0.26、0.23,P<0.05),淋巴细胞与前列腺体积呈负相关(r=-0.21,P<0.05)。结论糖尿病伴有前列腺体积增大患者年龄、淋巴细胞、PLR和MLR等临床参数与前列腺体积有关,为临床对于良性前列腺增生的预防和治疗提供重要的价值。

Objective To explore the correlation between clinical parameters,incluging age,hematological inflammatory parameters,and prostate volume in diabetic patients to provide insights into the prevention and treatment of benign prostatic hyperplasia.Methods We performed a retrospective analysis of 496 patients who were hospitalized in the Department of Endocrinology from February 2021 to June 2022 at the First Affiliated Hospital of Harbin Medical University with a diagnosis of diabetes mellitus by query from the test report processing system.They were grouped by whether the prostate volume was greater than or equal to 30ml,and divided into two groups:diabetes mellitus and without enlarged prostate volume(n=406),and diabetes mellitus with enlarged prostate volume(n=90).The patients'age,blood inflammation-related indexes,urine white blood cell count,and the patients'anterior and posterior diameter,upper and lower prostate diameter,and right and left diameter by abdominal ultrasound were collected.Results The differences of age,lymphocytes,monocytes,platelets,prostate volume and monocyte-to-lymphocyte ratio(MLR)were statistically significant between the two groups(P<0.05).In the correlation analysis of the clinical parameters among diabetic patients with enlarged prostate volume,age,platelet-to-lymphocyte ratio(PLR)and MLR were positively correlated with prostate volume(r were 0.24,0.26,0.23,P<0.05),and lymphocytes were negatively correlated with prostate volume(r=-0.21,P<0.05).Conclusion Clinical parameters such as age,lymphocytes,PLR,MLR and prostate volume in patients with diabetes mellitus with enlarged prostate volume are related to prostate volume,providing important clinical value for the treatment and prevention of benign prostatic hyperplasia.