星状神经节阻滞联合重复经颅磁刺激治疗卒中后失眠的临床效果

Clinical Effect of Stellate Ganglion Block Combined with Repetitive Transcranial Magnetic Stimulation in the Treatment of Post-stroke Insomnia

目的:探讨星状神经节阻滞治疗联合重复经颅磁刺激治疗卒中后失眠患者的效果。方法:选取2022年1月—2022年12月南宁市第一人民医院收治的卒中后失眠患者100例为观察对象,根据随机数字表法分为对照组和观察组,各50例。对照组采用星状神经节阻滞治疗,观察组在对照组基础上给予重复经颅磁刺激治疗。比较两组患者睡眠质量指数和相关睡眠质量指标,评估非快眼动睡眠(NREM)S1~S4值。结果:治疗后,观察组患者匹兹堡睡眠质量指数评分低于对照组,差异有统计学意义(P=0.012);治疗后,观察组患者睡眠总时间和快眼动睡眠时间均长于对照组,睡眠效率高于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者NREM S1、NREM S3、NREM S4值低于对照组,差异有统计学意义(P<0.05);治疗前后观察组NREM S2值均高于对照组,差异有统计学意义(P<0.05)。结论:应用星状神经节阻滞联合重复经颅磁刺激治疗卒中后失眠患者,可显著改善患者的睡眠质量。

Objective:To investigate the effect of stellate ganglion block therapy combined with repetitive transcranial magnetic stimulation in treating patients with post-stroke insomnia.Methods:One hundred cases of post-stroke insomnia patients admitted to Nanning First People's Hospital from January to December 2022 were selected for observation,and were divided into the con-trol group and the observation group according to the method of randomized numerical table,with fifty cases in each group.The control group was treated with stellate ganglion block,and the observation group was given repetitive transcranial magnetic stimula-tion treatment on the basis of the control group.The sleep quality index and related sleep quality indicators were compared be-tween the two groups,and the non-rapid eye movement sleep(NREM)S1 to 4 values were assessed.Results:After treatment,the Pittsburgh sleep quality index scores of patients in the observation group were lower than those of the control group,and the differ-ence was statistically significant(P=0.012);After treatment,the total sleep time and rapid eye movement sleep time of patients in the observation group were longer than that of the control group,and the sleep efficiency was higher than that of the control group,and the difference was statistically significant(P<0.05);After treatment,the NREM S1,NREM S3 and NREM S4 values of patients in the observation group were lower than those of the control group,and the difference was statistically significant(P<0.05);The NREMS2 values of the observation group before and after treatment were higher than those of the control group,and the difference was statistically significant(P<0.05).Conclusion:The application of stellate ganglion block combined with repetitive transcranial magnetic stimulation for the treatment of post-stroke insomnia patients can significantly improve the sleep quality of patients.