摘要
The endoplasmic reticulum(ER)functions as a quality-control organelle for protein homeostasis,or"proteostasis".The protein quality control systems involve ER-associated degradation,protein chaperons,and autophagy.
基金
This study was financially supported by The National Key Research and Development Program of China(grant number 2020YFC2008205)
The National Natural Science Foundation of China(grant numbers 82171058,81974134,and 81974137)
The Key R&D Plan of Hunan Province of China(No.2020SK2076)
Natural Science Foundation of Hunan Province(No.2019JJ40507 and 2023JJ30956).