摘要
Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,including altered iron homeostasis,reduced defense against oxidative stress,and abnormal lipid peroxidation.Recent studies have provided compelling evidence supporting the notion that ferroptosis plays a key pathogenic role in many diseases such as various cancer types,neurodegenerative disease,diseases involving tissue and/or organ injury,and inflammatory and infectious diseases.
基金
The authors received support from the National Natural Science Foundation of China(31970689 to J.M.,32330047,31930057 to F.W.,and 32100941 to S.S.)
the National Key R&D Program(2018YFA0507801 to J.M.and 2018YFA0507802 to F.W.).
