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Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2 被引量:1

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摘要 Hydroxycarboxylic acid receptor 2(HCAR2),a member of Class A G-protein-coupled receptor(GPCR)family,plays a pivotal role in anti-lipolytic and anti-inflammatory effects,establishing it as a significant therapeutic target for treating dyslipidemia and inflammatory diseases.
出处 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2023年第10期5059-5068,共10页 信号转导与靶向治疗(英文)
基金 This work was supported by the National Natural Science Foundation of China(32100988 to W.Y.,31972916 to Z.S,82271190 and 32100965 to L.C.) Science and Technology Department of Sichuan Province(2020YFQ0055 to P.F.and 2022ZYD0085 to Z.S.) Ministry of Technology Department of China grant(2019YFA0508800 to Z.S) 1.3.5 project for disciplines of excellence,West China Hospital,Sichuan University(ZYGD18027 to P.F,ZYYC20023 to Z.S).
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