缩宫素联合麦角新碱治疗高龄剖宫产产妇产后出血的效果

The effect of oxytocin combined with ergometrine in the treatment of postpartum hemorrhage in elderly cesarean sectionwomen

目的探讨缩宫素联合麦角新碱治疗高龄剖宫产产妇产后出血的效果。方法选取100例高龄剖宫产产后出血产妇为研究对象,随机分为两组,各50例。对照组采用缩宫素治疗,试验组采用缩宫素联合麦角新碱治疗,比较产后出血量、凝血功能及不良反应发生率。结果试验组产后2 h、产后24 h的出血量均少于对照组,差异有统计学意义(P<0.05);治疗后,试验组纤维蛋白原水平低于对照组,凝血酶原时间、凝血酶时间短于对照组,差异有统计学意义(P<0.05);试验组不良反应发生率为10.00%,对照组为8.00%,两组比较差异无统计学意义(P>0.05)。结论缩宫素联合麦角新碱治疗高龄剖宫产产妇产后出血,可减少出血量,优化凝血功能,安全性好,值得推广。

Objective To explore the effect of oxytocin combined with ergometrine in the treatment of postpartum hemorrhage in elderly cesarean section women.Methods 100 elderly postpartum hemorrhage women undergoing cesarean section were selected as the research subjects and randomly divided into two groups,with 50 cases in each group.The control group was treated with oxytocin,while the experimental group was treated with oxytocin combined with ergometrine.The postpartum bleeding volume,coagulation function,and incidence of adverse reactions were compared.Results The bleeding volume of the experimental group at 2 and 24 hours postpartum was lower than that of the control group,with a statistically significant difference(P<0.05);After treatment,the fibrinogen level in the experimental group was lower than that in the control group,and the prothrombin time and thrombin time were shorter than those in the control group,with statistically significant differences(P<0.05);The incidence of adverse reactions in the experimental group was 10.00%,while in the control group it was 8.00%.There was no statistically significant difference between the two groups(P>0.05).Conclusion The combination of oxytocin and ergometrine in the treatment of postpartum hemorrhage in elderly cesarean section women can reduce bleeding volume,optimize coagulation function,and have good safety,which is worth promoting.