海信CAS辅助下高强度聚焦超声消融治疗晚期胰腺癌效果

Effect of high-intensity focused ultrasound assisted by Hisense computer-assisted system in treatment of advanced pancreatic cancer

目的探讨海信计算机辅助系统(CAS)辅助下高强度聚焦超声(HIFU)治疗胰腺癌的效果。方法选取2020年1月-2021年5月于我院拟行HIFU治疗的22例胰腺癌患者。术前采用海信CAS将二维CT图像进行三维重建,明确胰腺肿瘤与周围肠道、脏器的毗邻关系,通过实体瘤疗效评价标准评价局部消融疗效,并记录患者术后并发症发生情况。结果海信CAS数字化三维重建结果可清晰显示胰腺肿瘤与周围肠道、脏器的毗邻关系,协助实现精准消融。22例胰腺癌患者中完全缓解率为9.1%,部分缓解率为68.2%,疾病稳定率为13.6%,疾病进展率为9.1%。所有患者在HIFU术后均未出现胃肠道穿孔、急性胰腺炎、胰瘘及消化道出血等严重并发症,仅1例患者出现浅Ⅱ度皮肤灼伤。结论海信CAS辅助下HIFU治疗晚期胰腺癌效果较好,值得在临床推广。

Objective To investigate the effect of high-intensity focused ultrasound(HIFU)assisted by Hisense compu-ter-assisted system(CAS)in the treatment of pancreatic cancer.Methods A total of 22 patients with pancreatic cancer who were scheduled to undergo HIFU in our hospital from January 2020 to May 2021 were enrolled.Before surgery,two-dimensional CT images were reconstructed into three-dimensional images using Hisense CAS,which were then used to clarify the adjacent relationship between pancreatic tumor and the surrounding intestinal tract and organs.Response Evaluation Criteria in Solid Tumors were used to evaluate the efficacy of local ablation,and postoperative complications were recorded.Results The results of three-dimensional digital reconstruction by Hisense CAS clearly displayed the adjacent relationship between pancreatic tumor and the surrounding intestinal tract and organs and helped to achieve precise ablation.The 22 patients with pancreatic cancer had a complete remission rate of 9.1%,a partial remission rate of 68.2%,a stable disease rate of 13.6%,and a progressive disease rate of 9.1%.No serious complications such as gastrointestinal perforation,acute pancreatitis,pancreatic fistula,and gastrointestinal bleeding were observed after HIFU,and only 1 patient had superficialⅡ-degree skin burn.Conclusion HIFU ablation assisted by Hisense CAS has a good clinical effect in the treatment of advanced pancreatic cancer and thus holds promise for clinical application.