基于液相色谱-质谱联用法的食品代谢组学研究进展

Research progress of liquid chromatography-mass spectrometry-based metabolomics in food science

随着经济全球化,食品工业也呈现出全球化发展趋势。随着人民生活水平的不断提高,人们更加关注食品的质量和安全,这就需要将新的技术和方法应用到食品科学研究领域。基于液相色谱-质谱的代谢组学是获取人类代谢组和研究食品科学的一种强有力的工具,在食品安全、食品质量、食品真实性和食品溯源方面发挥着重要的作用。食品分析中的靶向或非靶向代谢组学方法有着各自的优势和局限,选择与目标分析物相匹配的分析平台至关重要。该文综述了近年来基于液相色谱-质谱的代谢组学研究现状,并展望了食品代谢组学的最新应用趋势。

With the globalization of the economy,the food industry has also shown a global development trend.The continuous improvement of people's living standards makes people pay more attention to the quality and safety of food,which requires the application of new technologies and methods to the field of food science research.Liquid chromatography-mass spectrometry-based metabolomics is a powerful tool for obtaining human metabolome and studying food science,which plays an important role in food safety,food quality,food authenticity,and food traceability.Targeted or non-targeted metabolomics methods in food analysis have their advantages and limitations,and it is crucial to choose the appropriate analytical platform that matches the target analytes.This paper reviewed the current status of liquid chromatography-mass spectrometry-based metabolomics research in recent years and outlined the latest trends in the application of food metabolomics.