原发性脑出血血肿周边脑水肿的发生机制及药物治疗进展

Pathogenesis and drug treatment progress of peripheral cerebral edema in primary cerebral hemorrhage

原发性脑出血是临床常见的危急重症,血肿周边脑水肿是导致病情加重的重要病理生理过程,也是导致患者死亡的主要原因。血肿周边脑水肿发生可分为三个阶段,且不同阶段有相对应的发病机制,由于缺乏针对血肿本身的特异性治疗,因此对于血肿周边脑水肿的治疗是目前研究的热点。本文就近年来关于血肿周边脑水肿的分类、发生机制及药物治疗进展进行综述,以期为改善脑出血的临床疗效及预后提供借鉴。

Primary intracerebral hemorrhage is a common critical condition in clinic.Peripheral cerebral edema of hematoma is an important pathophysiological process leading to the exacerbation of the disease,and also the main cause of death.The occurrence of peripheral cerebral edema of hematoma can be divided into three stages,and different stages have corresponding pathogenesis.Due to the lack of specific treatment for hematoma itself,the treatment of peripheral cerebral edema of hematoma has become a hot research topic at present.This paper reviews the classification,pathogenesis and drug treatment of peripheral cerebral edema in recent years,in order to provide reference for improving the clinical efficacy and prognosis of cerebral hemorrhage.