街头无偿献血者ALT不合格人群及影响因素分析

Analysis of ALT Unqualified Population and Influencing Factors of Street Unpaid Blood Donors

目的 探析街头无偿献血者丙氨酸氨基转移酶(alanine aminotransferase, ALT)不合格人群的分布特征,找出其不合格的影响因素,以期为无偿献血的血液质量控制工作提供一定的参考。方法 本次研究选取2020年1月-2022年12月采集的街头无偿献血者75014例的血液检测资料进行回顾性分析,计算街头无偿献血者ALT不合格占比,并对ALT不合格人群的影响因素进行分析。结果 在75014例的街头无偿献血者中,ALT不合格率为2.72%(2044/75014),其中年龄、性别、体重、血型、学历、献血季节以及职业等因素不同时,ALT不合格率不同,差异有统计学意义(P<0.05)。结论 在街头无偿献血者中存在一定的ALT不合格样本,而ALT不合格人群的影响因素包括年龄、性别、体重、血型、学历、献血季节以及职业等,较为复杂;为降低街头无偿献血血液样本的报废率,提高工作效率,应根据其相关影响因素制定合理有效的干预措施,改善ALT不合格率。

Objective To explore distribution characteristics of alanine aminotransferase(ALT)unqualified population of street unpaid blood donors,identify related influencing factors,and provide some reference for blood quality control in voluntary blood donation.Methods The study chose blood test data of 75014 street voluntary blood donors from January 2020 to December 2022 for retrospective analysis,calculated ALT unqualified proportion of street voluntary blood donors,and analyzed related influencing factors.Result Among 75014 street voluntary blood donors,ALT failure rate was 2.72%(2044/75014),which varied with different factors including age,gender,weight,blood type,education,blood donation season,and occupation,difference was statistically significant(P<0.05).Conclusion There are some certain ALT unqualified samples among street unpaid blood donors,influencing factors of ALT unqualified population are relatively complex,including age,gender,weight,blood type,education,blood donation season,and occupation.to reduce sample scrap rate of streets unpaid blood donors,and improve work efficiency,reasonable and effective intervention measures should be developed based on relevant influencing factors to improve ALT failure rate.