盆底肌功能训练对女性性功能影响的系统评价和Meta分析

Effect of pelvic floor muscle training on female sexual function:a systematic review and Meta-analysis

目的:系统评价盆底肌功能训练(PFMT)对女性性功能的影响,并对现有证据进行Meta分析。方法:计算机检索中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方数据库、中文科技期刊数据库、MedLine、the Cochrane Library和Web of Science数据库和指南网有关以PFMT为主要干预手段的随机对照试验(RCT),检索时限均为从建库至2022年11月。由2位研究者独立筛选文献、提取资料并以Cochrane协作网对RCT的真实性评价工具评价纳入研究的偏倚风险后,采用RevMan 5.4软件进行统计分析。结果:Meta分析结果显示,PFMT对提高女性性功能总评分差异有统计学意义[WMD=1.90,95%CI(0.77,3.04),P<0.05]。在改善女性性唤起、性高潮、性满意、性交痛等方面,应用PFMT组优于对照组(P<0.05);在女性性欲方面无统计学意义(P=0.13);对女性阴道湿润度的影响尚不能判断。结论:现有证据表明,PFMT能从多个方面提高女性性功能。

Objective:The aim of this study was to systematically review the effect of pelvic floor muscle training(PFMT)on female sexual function and to conduct a Meta-analysis of available evidence.Methods:The randomized controlled trials with PFMT as the main intervention were retrieval from CBM,CNKI,WanFang Database,VIP,MedLine,the Cochrane Library,Web of Science,and guide network.The retrieval time was from the inception to November 2022.Two independent researchers screened the archives,extracted the data and evaluated the bias risk of selected articles with the Cochrane handbook for systematic reviews of interventions.The data were analyzed using the RevMan 5.4.Results:PFMT had statistical difference in improving the total score of female sexual function(WMD=1.90,95%CI 0.77-3.04,P<0.05).The application of PFMT was better than the control group in improving female sexual arousal(P<0.05),orgasm(P<0.05),sexual satisfaction(P<0.05)and dyspareunia(P<0.05),there was no significant difference in female libido(P=0.13).The impact on vaginal wetness cannot be analyzed.Conclusion:Current evidence shows that PFMT can improve female sexual function from many aspects.