天然低共熔溶剂提取黄酮类化合物的研究进展

Research Progress on Extraction of Flavonoids Using Natural Deep Eutectic Solvents

天然低共熔溶剂是一种新型绿色溶剂,有望替代传统有机溶剂实现对黄酮等天然产物的高效提取。为了阐明天然低共熔溶剂在黄酮化合物萃取方面的应用,本文对近5年发表的相关研究论文进行了整理和分析,综述了天然低共熔溶剂提取黄酮的研究现状,并详细讨论了影响提取率的各种因素。天然低共熔溶剂在黄酮、黄酮醇、二氢黄酮、花色素、异黄酮等多类天然黄酮产物的提取方面表现良好,其萃取率普遍优于甲醇、乙醇等传统溶剂,且萃取产物活性更高;低共熔溶剂的组成、摩尔比、含水量和温度等条件会显著影响其对黄酮化合物的萃取。文章还对天然低共熔溶剂在未来的发展趋势作出展望,希望能为黄酮化合物的高效、绿色提取提供有益参考。

The natural deep eutectic solvent is a new type of green solvent that is expected to replace traditional organic solvents for efficient extraction of natural products such as flavonoids.In order to clarify the application of natural deep eutectic solvents in the extraction of flavonoids,the author summarizes and analyzes relevant research papers published in the past 5 years.This article provides a review of the current research status of natural deep eutectic solvents for extracting flavonoids,and discuss in detail the various factors that affect the extraction rate.The natural deep eutectic solvents perform well in the extraction of various natural flavonoid products such as flavonoids,flavonols,flavonones,anthocyans,and isoflavones.Their extraction rates are generally better than traditional solvents such as methanol and ethanol,and the extracted products have higher activity.The composition,molar ratio,water content,and temperature of deep eutectic solvents significantly affect their extraction of flavonoids.Finally,the development trend of natural eutectic solvents in the future is prospected.This paper aims to provide reference for the efficient and green extraction of flavonoids.