掩味用辅料及其应用

Taste masking pharmaceutical excipients and their applications

药物的口感对患者的顺应性有着重要的影响,但大多数活性药物成分具有让人不适的口感,尤其是中药材。通过各种掩味性能的药用辅料结合相应技术可以改善药品口感和其他剂型特征,从而提高患者顺应性。本文主要通过对掩味用辅料进行汇总,从辅料角度解释掩味机制并介绍相关用途,为儿童制剂掩味的进一步研究提供参考。

The taste of drugs has an important impact on the compliance of patients,but most of the active drug ingredients have an uncomfortable taste,especially traditional Chinese medicine.Through a variety of pharmaceutical excipients with taste masking properties combined with corresponding technologies can improve the taste of drugs and the characteristics of other dosage forms,so as to improve patient compliance.Here,we mainly summarize the auxiliary materials used for taste masking,explain the mechanism of taste masking from the point of view of excipients and introduces related uses,so as to provide reference for further research on taste masking of pediatric preparations.