解痉药应用于消化内镜检查的研究进展

Progress of Research on Application of Antispasmodics in Digestive Endoscopy

在消化内镜检查过程中,合理利用解痉药可减轻胃肠道蠕动,是提高内镜图像清晰度和诊断精确度的有效临床策略。目前胃肠镜检查中常用的解痉药主要包括全身解痉药和局部解痉药。全身解痉药存在使用不便、禁忌证和不良反应较多等局限性。局部解痉药通过口服或喷洒,直接作用于消化道黏膜,可快速有效地抑制蠕动,临床使用便捷,不良反应较少。本文简要综述全身和局部解痉药的作用机制、解痉疗效,以及在消化内镜中的应用方式,旨在为消化内镜医师进行检查时提供解痉药选择策略。

Reasonable use of antispasmodics to attenuate gastrointestinal peristalsis during digestive endoscopy is an effective clinical strategy to improve the clarity of endoscopic images and diagnostic accuracy.The commonly used antispasmodics in gastroenteroscopy mainly include systemic antispasmodics and local antispasmodics at present.Systemic antispasmodics have some limitations,such as inconvenience in usage,many contraindications and adverse reactions.Local antispasmodics can act directly on the digestive tract mucosa by oral administration or spraying,which can quickly and effectively inhibit peristalsis,and is convenient for clinical use with fewer adverse reactions.This review summarizes the mechanism of action,efficacy and application of systemic antispasmodics and local antispasmodics in digestive endoscopy,in order to provide strategies for the selection of antispasmodics in digestive endoscopy.