针刺联合益气化瘀方治疗气虚血瘀型子宫内膜异位症的临床观察

Clinical Observation on the Acupuncture Combined with Yiqi Huayu Prescription in Patients with Endometriosis

【目的】观察针刺联合益气化瘀方治疗气虚血瘀型子宫内膜异位症的临床疗效。【方法】将80例气虚血瘀型子宫内膜异位症患者随机分为观察组和对照组,每组各40例,对照组给予针刺治疗,观察组给予针刺联合益气化瘀方治疗。4周为1个疗程,连续治疗3个疗程。治疗3个月后,评价2组临床疗效,观察2组患者治疗前后中医证候积分的变化情况,以及卵泡生成激素(FSH)、雌二醇(E2)水平的情况。比较2组患者治疗前后子宫内膜血流搏动指数(PI)、阻力指数(RI)水平的变化情况。并评估2组患者子宫内膜异位症患者生存质量量表(EHP-5)评分的变化情况。【结果】(1)观察组总有效率为97.50%(39/40),对照组为80.00%(32/40)。观察组疗效优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者的中医证候积分明显改善(P<0.05),且观察组在改善中医证候积分方面明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗后,2组患者的FSH与E2水平明显改善(P<0.05),且观察组在改善FSH与E2水平方面明显优于对照组,差异有统计学意义(P<0.05)。(4)治疗后,2组患者的PI与RI水平明显改善(P<0.05),且观察组在改善PI与RI水平方面明显优于对照组,差异有统计学意义(P<0.05)。(5)治疗后,2组患者的EHP-5评分明显改善(P<0.05),且观察组在改善EHP-5评分方面明显优于对照组,差异有统计学意义(P<0.05)。【结论】针刺联合益气化瘀方治疗子宫内膜异位症,能明显改善患者的血流动力学状态,减轻患者的临床症状,减低疾病对卵巢功能的影响,从而提高患者生活质量,疗效显著。

Objective To observe the clinical efficacy of acupuncture combined with Yiqi Huayu Prescription(mainly with the functions of replenishing qi and resolving stasis)in treating endometriosis of qi deficiency and blood stasis type.Methods Eighty patients with qi deficiency and blood stasis type of endometriosis were randomly divided into observation group and control group,40 patients in each group.The control group was treated with acupuncture,and the observation group was treated with acupuncture combined with Yiqi Huayu Prescription.Both groups were treated for 3 consecutive courses and 4 weeks as a course of treatment.After 3 months of treatment,the clinical efficacy of the two groups was evaluated,and the changes in the traditional Chinese medicine(TCM)scores and the levels of follicle-stimulating hormone(FSH)and estradiol(E2)were observed before and after treatment.The changes of endometrial pulsatility index(PI)and resistance index(RI)were compared before and after treatment in the two groups,and the changes in the endometriosis patient survival quality scale(EHP-5)score of the two groups of patients were assessed.Results(1)The total effective rate of the observation group was 97.50%(39/40),and the control group was 80.00%(32/40).The efficacy of the observation group was superior to that of the control group,and the difference was statistically significant(P<0.05).(2)After treatment,the TCM syndrome scores of patients in the two groups were significantly improved(P<0.05),and the observation group was significantly superior to the control group in improving TCM syndrome scores,and the difference was statistically significant(P<0.05).(3)After treatment,the FSH and E2 levels of patients in the two groups were significantly improved(P<0.05),and the observation group was significantly superior to the control group in improving the FSH and E2 levels,and the difference was statistically significant(P<0.05).(4)After treatment,the PI and RI levels of patients in the two groups were significantly improved(P<0.05),and the observation groupwassignificantlysuperior to the control group in improving PI and RI levels,and the difference was statistically significant(P<0.05).(5)After treatment,the EHP-5 scores of patients in the two groups were significantly improved(P<0.05),and the observation group was significantly superior to the control group in improving the EHP-5 scores,and the difference was statistically significant(P<0.05).Conclusion Acupuncture combined with Yiqi Huayu Prescription exerts certain effect in treating qi deficiency and blood stasis type of endometriosis,can significantly improve the haemodynamic status of patients,reduce the clinical symptoms of patients,and diminish the impact of the disease on the ovarian function,so as to improve the quality of life of the patients.