摘要
糖尿病肾脏疾病是糖尿病严重的微血管并发症之一,病因复杂,机制繁多,病程较长且预后较差,给患者的生活带来极大的威胁。近年来,关于肠道菌群的研究越来越深入,肠-肾轴理论进入糖尿病肾脏疾病领域,带来新的治疗理念。本文综述了肠道菌群在糖尿病肾脏疾病发生发展中的作用,并探讨了肠道菌群治疗糖尿病肾脏疾病的潜在治疗策略。
Diabetic kidney disease is a severe microvascular complication of diabetes characterized by complex etiology,diverse mechanisms,long course,and poor prognosis,posing a significant threat to patients′quality of life.In recent years,research on gut microbiota has progressed deeper,and the concept of the gut-kidney axis emerges,introducing novel therapeutic concepts.This article provides an overview of the role of gut microbiota in the development of diabetic kidney disease and explores potential therapeutic strategies involving gut microbiota for the treatment of this condition.
作者
郑楠
邓欣如
汤莎莎
袁慧娟
Zheng Nan;Deng Xinru;Tang Shasha;Yuan Huijuan(Department of Endocrinology and Metabolism,Zhengzhou University People′s Hospital,Henan Provincial People′s Hospital,Zhengzhou 450003,China;Department of Endocrinology and Metabolism,Henan Provincial People′s Hospital,Zhengzhou 450003,China)
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2023年第10期899-904,共6页
Chinese Journal of Endocrinology and Metabolism
基金
国家自然科学基金(82270865、81970705)。
关键词
糖尿病肾脏疾病
肠道菌群
机制
治疗
Diabetic kidney disease
Gut microbiota
Mechanism
Treatment
