胆囊管癌的临床特点及其手术治疗要点

Clinicopathological characteristics and key points in surgical treatment for cystic duct carcinoma

虽然胆囊管属于胆囊的一部分,但胆囊管癌与胆囊癌存在诸多不同的临床病理学特点,包括肿瘤分型、人口学特征、临床表现、影像学及病理学特点。根治性手术切除(R0切除)是胆囊管癌首选的治疗手段,也是唯一有治愈希望的方法,因此对于无远处转移、全身情况良好的胆囊管癌病人应该积极实施以根治为目的的切除手术。具体手术治疗方式应根据肿瘤侵犯的范围而定。临床上对胆囊管癌的认识尚存在一些争议,有待进一步积累更多更大宗的多中心临床研究结果,以及进一步探索阐明其肿瘤生物学行为特点。

Although the cystic duct belongs to one part of the gallbladder,there exist differences in clinicopathological features between cystic duct carcinoma and gallbladder carcinoma,including tumor classification,demographic features,clinical manifestations,imaging,and pathological features.Radical(R0) resection remains the treatment of choice and the only hope of cure for cystic duct carcinoma.Hence,R0 resection should be attempted in patients with good general conditions and the absence of distant metastases.The surgical pattern should be adopted on the basis of tumor extent.There are still some controversies in the clinical understanding of cystic duct carcinoma,and it is necessary to further accumulate more and larger multi-center clinical research results,and further explore and elucidate the biological behavior characteristics of cystic duct carcinoma.