摘要
自身免疫病实验诊断在疾病预警、诊断、预后评估及疗效监测等方面面临着许多机遇和挑战。无论是经典的抗核抗体,还是新型的抗药物抗体、细胞因子、自身免疫病合并感染和肿瘤的新型自身抗体等标志物,都亟须规范化及标准化相关生物标志物的临床应用,不断扩展新型标志物的应用场景,进一步探究相关生物标志物的临床意义,以推进自身免疫病领域检验医学的高质量发展。
Laboratory biomarkers of autoimmune diseases have faced promising prospects and challenges in various aspects of clinical application,including disease warning,diagnosis,prognostic evaluation,and therapeutic monitoring.There is an urgent need for standardization of clinical applications of relevant biomarkers,such as antinuclear antibodies,antidrug antibodies,immune disease-associated cytokines,and novel autoantibodies associated with autoimmune diseases complicated with infection,and malignancy.It is imperative to expand the application scenarios and explore the potential applications of novel biomarkers in order to promote the high-quality development of laboratory medicine in the field of autoimmune diseases.
作者
李永哲
Li Yongzhe(Department of Clinical Laboratory,Peking Union Medical College Hospital,Chinese Academy of Medical Science and Peking Union Medical College,State Key Laboratory of Complex,Severe and Rare Diseases,Beijing 100730,China)
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2023年第11期1109-1112,共4页
Chinese Journal of Laboratory Medicine
基金
国家重点发展计划(2018YFE0207300)
北京市自然科学基金(M23008)
中央高水平医院临床科研业务(2022-PUMCH-B-124)。